G-Furosemide 20 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 9.00 (2 x 5: ৳ 90.00)

Medicine Details

Category Details
Generic Furosemide
Company Gonoshasthaya pharma ltd
Also available as
G furosemide 40 mg tablet G furosemide 250 mg tablet

Indications

  • Fluid retention associated with chronic congestive cardiac failure
  • Fluid retention associated with acute congestive cardiac failure
  • Fluid retention associated with chronic renal failure
  • Maintenance of fluid excretion in acute renal failure
  • Fluid retention associated with nephrotic syndrome
  • Fluid retention associated with liver disease
  • Hypertension
  • Hypertensive crisis
  • Support of forced diuresis

Pharmacology

  • Monosulphonyl diuretic
  • Effective in low glomerular filtration rate
  • Distinctive action on renal tubular function
  • Prompts onset of action
  • Inhibition of sodium and chloride transport in the ascending limb of the loop of Henle
  • Independence of action from acid-base balance changes
  • Rapid absorption from gastrointestinal tract
  • Considerable proportions bound to plasma proteins
  • Rapid excretion in the urine

Dosage & Administration

  • Initial adult dose of 40mg daily
  • Reduced to 20mg daily or 40mg on alternate days
  • Daily doses of 80mg or higher may be required
  • Dose titration up to 600mg/day
  • Dose for children and elderly
  • Dosage for hypertension
  • Starting dose of 250mg for selected patients with advanced chronic renal failure
  • Dosage for Furosemide syrup
  • Dosage for Furosemide injection

Interaction

  • Marked fall in blood pressure when ACE inhibitors are added
  • Increased serum lithium levels
  • Enhanced toxic effects of nephrotoxic antibiotics

Contraindications

  • Contraindicated in anuria
  • Electrolyte deficiency
  • Pre-comatose states associated with liver cirrhosis
  • Hypersensitivity to furosemide or sulphonamides

Side Effects

  • Disturbed electrolytes and water balance
  • Alkalosis
  • Uric acid retention
  • Provocation of hyperglycemia and glycosuria

Pregnancy & Lactation

  • Pregnancy category C
  • Caution in cardiogenic shock and first trimester of pregnancy
  • Monitoring of blood pressure and pulse during rapid diuresis
  • Caution in nursing mothers

Precautions & Warnings

  • Increased risk of acute retention in patients with prostatic hypertrophy
  • Risk of undesirably pronounced fall in blood pressure
  • Impairment of ability to concentrate and react
  • Risk during driving or performing hazardous tasks

Overdose Effects

  • Clinical picture depends on electrolyte and fluid loss
  • Signs such as hypovolaemia, dehydration, cardiac arrhythmias
  • Management includes limiting systemic absorption and gastric lavage

Therapeutic Class

  • Loop diuretics

Storage Conditions

  • Protect from light
  • Do not use past expiry date
  • Keep out of the reach of children
  • To be dispensed only on the prescription of a registered physician

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