Jakloc 5 mg (Tablet)

Unit Price: ৳ 48.00 (1 x 10: ৳ 480.00)
Strip Price: ৳ 480.00

Medicine Details

Category Details
Generic Tofacitinib
Company Popular pharmaceuticals ltd
Also available as
Jakloc xr 11 mg tablet

Indications

  • Rheumatoid Arthritis
  • Psoriatic Arthritis
  • Ulcerative Colitis

Pharmacology

  • Autoimmune disease
  • Pro-inflammatory cytokines
  • JAK-STAT pathway
  • Immune cell function

Dosage & Administration

  • Tofacitinib 5 mg twice daily
  • Tofacitinib 11 mg once daily
  • Moderate and severe renal impairment
  • Moderate hepatic impairment

Interaction

  • Inhibitors of Cytochrome P450 3A4 (CYP3A4)
  • Potent inhibition of CYP2C19
  • Potent CYP inducers (e.g. Rifampin)

Side Effects

  • Upper respiratory tract infections
  • Headache
  • Diarrhea
  • Nasopharyngitis

Pregnancy & Lactation

  • Pregnancy Category C
  • Excretion in human milk
  • Adverse reactions in nursing infants

Precautions & Warnings

  • Serious Infections
  • Gastrointestinal Perforations
  • Laboratory Monitoring
  • Immunizations
  • Absolute lymphocyte count
  • Absolute neutrophil count
  • Hemoglobin

Use in Special Populations

  • Pediatric Use
  • Geriatric Use
  • Renal impairment
  • Hepatic impairment

Therapeutic Class

  • Immunosuppressant

Storage Conditions

  • Below 30°C
  • Protection from light & moisture
  • Keep out of the reach of children

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