Lasix 20 mg/2 ml (IM/IV Injection)
Medicine Details
| Category | Details |
|---|---|
| Generic | Furosemide |
| Company | Synovia pharma plc |
| Also available as |
Title
Furosemide 40 mg Tablet
Categories
- Diuretic
- Antihypertensive
- Loop diuretics
Description
Furosemide is indicated for fluid retention associated with chronic congestive cardiac failure, acute congestive cardiac failure, chronic renal failure, maintenance of fluid excretion in acute renal failure, hypertension, hypertensive crisis, and more.
Dosage
- 40 mg tablet
- 250 mg tablet
- Syrup
- Injection
Administration
- Initial adult dose is 40 mg daily
- Doses of 80-120 mg daily may be required for resistant edema
- For selected patients with advanced chronic renal failure, diuretic therapy may be started with Furosemide orally
- Furosemide liquid has an exceptionally wide therapeutic range
- Doses of 20-50 mg intramuscularly or intravenously may be given initially for edema
Pharmacology
Furosemide is a monosulphonyl diuretic with distinctive action on renal tubular function and affects a peak diuresis; rapid onset of action and inhibition of sodium and chloride transport in the ascending limb of the loop of Henle
Interaction
A marked fall in blood pressure may be seen when ACE inhibitors are added to Lasix therapy; serum lithium levels may be increased; toxic effects of nephrotoxic antibiotics may be increased by concomitant administration of potent diuretics
Contraindications
Anuria, electrolyte deficiency, pre-comatose states associated with liver cirrhosis, hypersensitivity to furosemide or sulphonamides
Side Effects
Disturbed electrolytes and water balance, alkalosis, uric acid retention, acute gout, hyperglycemia, glycosuria
Pregnancy & Lactation
Pregnancy category C; cautious use in cardiogenic shock and first trimester of pregnancy; caution in patients liable to electrolyte deficiency; may inhibit lactation or pass into breast milk
Precautions & Warnings
Increased risk of developing acute retention in patients with prostatic hypertrophy; risk of undesirably pronounced fall in blood pressure; impair patient's ability to concentrate and react
Overdose Effects
Clinical picture depends primarily on the extent and consequences of electrolyte and fluid loss; management involves attempts to limit further systemic absorption of the active ingredient
Therapeutic Class
Loop diuretics
Storage Conditions
Protect from light; do not use it later than the date of expiry; keep all medicines out of the reach of children; to be dispensed only on the prescription of a registered physician