Ciafil 10 mg (Tablet)

Unit Price: ৳ 35.00 (1 x 4: ৳ 140.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Tadalafil
Company Navana pharmaceuticals ltd
Also available as
Ciafil 20 mg tablet

Indications

  • Erectile Dysfunction (ED)
  • Benign Prostatic Hyperplasia (BPH)
  • Both Erectile Dysfunction and BPH

Pharmacology

Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor. It increases cGMP in smooth muscle cells, causing smooth muscle relaxation and increased blood flow into the corpus cavernosum, leading to penile erection. It also relaxes smooth muscle in the prostate and bladder, improving blood flow to the urinary tract and widening the opening of the bladder neck for improved voiding.

Dosage & Administration

  • Erectile Dysfunction: Recommended starting dose is 10 mg, with a maximum of 20 mg or a minimum of 5 mg once daily.
  • Benign prostatic hyperplasia: Recommended dose is 5 mg taken at the same time every day.
  • Combined Erectile Dysfunction and BPH: Recommended dose is 5 mg at the same time every day.

Interaction

  • Nitrates (e.g., Isosorbide, Nitroglycerin)
  • Alpha adrenergic blockers
  • Antihypertensives
  • Alcohol
  • Antacids (magnesium hydroxide/aluminum hydroxide)
  • Ketoconazole
  • Ritonavir
  • Erythromycin
  • Itraconazole
  • Grapefruit juice
  • HIV protease inhibitors
  • Rifampin
  • Carbamazepine
  • Phenytoin
  • Phenobarbital

Contraindications

  • Use of Nitrates
  • Hypersensitivity reactions to Tadalafil

Side Effects

  • Headache
  • Dyspepsia
  • Back pain
  • Myalgia
  • Nasal pharyngitis
  • Nasal congestion
  • Change in Color Vision
  • Sudden vision loss
  • Hearing loss
  • Stevens-Johnson Syndrome
  • Exfoliative dermatitis
  • Angina
  • Stroke
  • Myocardial infarction
  • Severe hypotension
  • Tachycardia

Pregnancy & Lactation

Tadalafil is categorized as pregnancy category B by the USFDA, recommended for use during pregnancy when benefit outweighs risk. Caution is advised when administering tadalafil to nursing women due to lack of data on excretion in human milk.

Precautions & Warnings

  • Angina
  • Renal impairment
  • Hepatic impairment
  • Bleeding concomitant with Nitrates
  • Alpha Blockers
  • Alcohol
  • CYP3A4 Inhibitors
  • Other PDE5 inhibitors

Therapeutic Class

Drugs for Erectile Dysfunction

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

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