Torcox 120 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Title

Torcox 120 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

Torcox 120 mg Tablet is a selective COX-2 inhibitor indicated for the symptomatic relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, acute gouty arthritis, and moderate pain associated with dental surgery.

Indication

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

Etoricoxib is a potent COX-2 specific inhibitor, decreasing clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation.

DosageAdministration

  • AdultAdolescentOver16Years:
    • Osteoarthritis:
      • 30 mg once daily
      • 60 mg once daily if insufficient relief
    • RheumatoidArthritis: 90 mg once daily
    • AnkylosingSpondylitis: 90 mg once daily
    • AcuteGoutyArthritis: 120 mg once daily for 8 days
    • PostoperativeDentalSurgeryPain: 90 mg once daily, limited to a maximum of 3 days

Interactions

  • Oral anticoagulants
  • Diuretics
  • ACE inhibitors
  • Angiotensin II Antagonists
  • Acetylsalicylic Acid
  • Ciclosporin
  • Tacrolimus
  • Lithium

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or GI bleeding
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension
  • Ischaemic heart disease
  • Peripheral arterial disease
  • Cerebrovascular disease

SideEffects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Appetite and weight change
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Mental acuity impaired
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia and arthralgia
  • Confusion
  • Hallucinations

PregnancyLactation

Not recommended during conception, excreted in the milk of lactating rats

PrecautionsWarnings

  • Caution with elderly, prior history of gastrointestinal disease
  • Caution with cardiovascular risk factors
  • Monitoring of renal function
  • Caution with cardiac failure, left ventricular dysfunction, hypertension, edema
  • Monitoring of liver function
  • Discontinue at first appearance of hypersensitivity

OverdoseEffects

No significant toxicity reported up to 150 mg/day, general supportive measures to be employed in case of overdose

TherapeuticClass

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

StorageConditions

Store below 30°C, protect from light & moisture, keep out of reach of children

ChemicalStructure

  • MolecularFormula: C18H15ClN2O2S
  • ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

CommonlyAskedQuestions

  • UsesDurationEffect: 20-24 hours
  • OnsetAction: 1-2 hours, faster when taken without food
  • PregnancyWarnings: 1
  • HabitForming:
  • BreastfeedingWarnings: 1
  • AlcoholInteractions: Unsafe
  • DrivingSafety: May affect alertness
  • KidneyFunction: Caution in patients with kidney disease
  • LiverFunction: Caution in patients with liver disease
  • QuickTips:
    • Relieves pain and inflammation
    • May cause fewer stomach problems compared to other NSAIDs
    • May cause dizziness and fatigue, avoid driving
    • Do not consume alcohol while on treatment
    • Regularly monitor blood pressure during treatment
    • Inform doctor of history of ulcers, heart diseases, high blood pressure, liver or kidney disease

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