Dytor 5 mg (Tablet)

Indications

• Management of edema of cardiac, renal, and hepatic origin
• Management of hypertension
• Sole therapeutic agent for hypertension
• Combination therapy for hypertension

Pharmacology

• Inhibition of Na+/K+/2Cl- carrier system
• Increase in delivery of tubular fluid and electrolytes
• Decrease in reabsorption of sodium and chloride
• Increase in aldosterone production
• Increase in urinary excretion of sodium, chloride, and water
• Temporary reduction in blood pressure
• Temporary decrease in cardiac output

Dosage & Administration

• Usual initial oral dose for congestive heart failure
• Usual initial oral dose for chronic renal failure
• Usual initial oral dose for hepatic cirrhosis
• Usual initial oral dose for hypertension
• Titration of dose for inadequate diuretic response

Interaction

• Increased risk of severe hypokalemia with specific medications
• Increased risk of lithium toxicity
• Increased potential for ototoxicity and nephrotoxicity with specific medications
• Increased risk of toxicity with digoxin
• Reduced diuretic effect with NSAIDs
• Increased risk of hypotension with antihypertensives

Contraindications

• Known hypersensitivity to torasemide and other sulfonyl ureas
• Anuria

Side Effects

• Dry mouth
• Dizziness
• Tiredness
• Skin rash
• Diarrhea
• Constipation
• Nausea
• Vomiting
• Orthostatic hypotension
• Muscle cramp
• Mild and transient side effects

Pregnancy & Lactation

• Limited studies in pregnant women
• Use during pregnancy only if clearly needed
• Unknown excretion in human milk
• Caution during administration to nursing mothers

Precautions & Warnings

• Precautions for diabetes
• Precautions for gout
• Precautions for hypotension
• Precautions for liver failure

Use in Special Populations

• Safety and efficacy not established in children

Overdose Effects

• Signs and symptoms of excessive pharmacological effect
• Dehydration
• Hypovolemia
• Hypokalemia
• Fluid and electrolyte supplement for treatment

Therapeutic Class

• Loop diuretics

Storage Conditions

• Room temperature storage
• Cool and dry place
• Protection from moisture and sunlight
• Keep out of reach of children

Related Brands

• Dytor 2.5 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd