Esprazo 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Esomeprazole
Company Pacific pharmaceuticals ltd
Also available as
Esprazo 20 mg tablet

Title

Esprazo 20 mg Capsule

Categories

Medicine, Gastrointestinal Health

Description

Esprazo is a proton pump inhibitor indicated for relieving chronic heartburn symptoms, healing erosive esophagitis, maintenance of healing, H. Pylori eradication, Zollinger-Ellison Syndrome, dyspepsia, and ulcers.

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • H. Pylori eradication
  • Zollinger-Ellison Syndrome
  • Acid-related dyspepsia
  • Duodenal and gastric ulcer

Pharmacology

  • Proton pump inhibitor suppressing gastric acid secretion
  • Specific inhibition of H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Plasma protein binding
  • Metabolized by CYP2C19 and CYP3A4
  • Excretion in urine and feces

Dosage

  • Healing of Erosive Esophagitis: 20 mg or 40 mg once daily for 4-8 weeks
  • Symptomatic GERD: 20 mg once daily for 4 weeks
  • H. Pylori eradication: Triple therapy with esomeprazole 40 mg once daily for 10 days
  • Zollinger-Ellison Syndrome: Dose of 20-80 mg once daily
  • Acid-related Dyspepsia: 20-40 mg once daily for 2-4 weeks
  • Duodenal and Gastric Ulcer: 20 mg once daily for 2-8 weeks
  • IV injection dosage for adult and pediatric patients
  • Risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy in adults

Administration

  • Swallow tablet or capsule whole and take one hour before a meal
  • Oral suspension preparation and administration
  • IV injection preparation and administration

Interaction

  • Extensive metabolism by CYP2C19 and CYP3A4
  • Likely interference with absorption of drugs affected by gastric pH
  • Co-administration effects with clarithromycin
  • No significant interactions with certain drugs

Contraindications

Hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not preclude gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • Use of antacids while taking Esprazo

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy in geriatric use
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in renal impairment

Overdose Effects

  • Acute toxicity symptoms in rats
  • No reports of overdose with Esprazo
  • Symptomatic and supportive treatment recommended in case of overdose

Storage Conditions

Store at a temperature not exceeding 30°C in a dry place, protect from light and moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions

  • Uses of Esprazo 20 mg Capsule
  • Side effects of Esprazo 20 mg Capsule
  • Pregnancy and breastfeeding considerations
  • Time to onset of action
  • Quick tips for using Esprazo 20 mg Capsule

Related Brands