Luretic 5 mg (Tablet)
Unit Price: ৳ 3.50 (5 x 10: ৳ 175.00)
Strip Price: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Torasemide |
| Company | Drug international ltd |
| Also available as |
Indications
- Management of edema of cardiac, renal and hepatic origin
- Management of hypertension
- Sole therapeutic agent for hypertension
- Combination therapy for hypertension
Pharmacology
- Inhibition of Na+/K+/2Cl- carrier system
- Decrease in reabsorption of sodium and chloride
- Increase in delivery of tubular fluid and electrolytes
- Increase in aldosterone production
- Increased sodium reabsorption at distal tubules
- Increase in urinary excretion of sodium, chloride, and water
- Diuretic actions leading to reduced extracellular and plasma fluid volume
- Temporary reduction in blood pressure and cardiac output
Dosage & Administration
- Usual initial oral doses for congestive heart failure, chronic renal failure, hepatic cirrhosis, and hypertension
- Titration of dose based on diuretic response
- Guidelines for single doses
- Steps for dose adjustment
- Duration for assessing blood pressure reduction
Interaction
- Hypokalaemia risk with specific medications
- Increased risk of lithium toxicity
- Potential for ototoxicity and nephrotoxicity with certain medications
- Increased risk of toxicity with digoxin
- Reduced diuretic effect with NSAIDs
- Increased risk of hypotension with antihypertensives
Contraindications
- Known hypersensitivity to torasemide and sulfonyl ureas
- Anuria
Side Effects
- Possible side effects such as dry mouth, dizziness, tiredness, skin rash, diarrhea, constipation, nausea, vomiting, orthostatic hypotension, and muscle cramps
- Mild and transient nature of side effects
Pregnancy & Lactation
- Lack of adequate and well-controlled studies in pregnant women
- Cautionary use during pregnancy if clearly needed
- Unknown excretion in human milk
- Cautionary use during lactation
Precautions & Warnings
- Special precautions for diabetes, gout, hypotension, and liver failure
Use in Special Populations
- Absence of established safety and efficacy in children
Overdose Effects
- Anticipated signs and symptoms of excessive pharmacological effect
- Possible effects including dehydration, hypovolemia, hypotension, and hypokalemia
- Recommended treatment of overdose with fluid and electrolyte supplement
Therapeutic Class
- Belongs to loop diuretics category
Storage Conditions
- Recommended storage at room temperature less than 30°C
- Protection from moisture and sunlight
- Safety measures to keep the medicine out of children's reach