Frudema 40 mg (Tablet)
Unit Price: ৳ 0.53 (10 x 10: ৳ 53.00)
Strip Price: ৳ 5.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Furosemide |
| Company | Pacific pharmaceuticals ltd |
Title
- Frudema Furosemide Tablet
Categories
- Diuretic
- Antihypertensive
- Loop Diuretic
Description
- Frudema is indicated for fluid retention associated with chronic congestive cardiac failure, acute congestive cardiac failure, chronic renal failure, maintenance of fluid excretion in acute renal failure, fluid retention associated with nephrotic syndrome, fluid retention associated with liver disease, hypertension, hypertensive crisis, and support of forced diuresis.
DosageAndAdministration
- Initial adult dose is 40 mg daily, reduced to 20 mg daily or 40 mg on alternate days. For resistant edema, 80-120 mg daily. Children doses vary based on age and condition. The dose of furosemide may be carefully titrated up to 600 mg/day for clinically severe edematous states. The usual initial dose of furosemide for hypertension is 80 mg, usually divided into 40 mg twice a day.
ModeOfAction
- Furosemide is a monosulphonyl diuretic with a distinctive action on renal tubular function. It affects a peak diuresis far greater than that observed with other agents. It acts primarily to inhibit electrolyte reabsorption in the thick ascending limb of the loop of Henle.
Interaction
- A marked fall in blood pressure may be seen when ACE inhibitors are added to Frudema therapy. Serum lithium levels may be increased when lithium is given concomitantly with Frudema. The toxic effects of nephrotoxic antibiotics may be increased by concomitant administration of potent diuretics such as Frudema.
Contraindications
- Furosemide is contraindicated in anuria, electrolyte deficiency, pre-comatose states associated with liver cirrhosis, and in cases of hypersensitivity to furosemide or sulphonamides.
SideEffects
- Electrolytes and water balance may be disturbed as a result of diuresis of prolonged therapy. Prolonged use can produce alkalosis. It may also cause uric acid retention and may rarely produce acute gout. Frudema may provoke hyperglycemia and glycosuria.
PregnancyAndLactation
- Pregnancy category C. Furosemide should be cautiously used in cardiogenic shock complicated by pulmonary edema and in the first trimester of pregnancy. Blood pressure and pulse during rapid diuresis should be monitored. Caution should be observed in patients liable to electrolyte deficiency.
PrecautionsAndWarnings
- Patients with prostatic hypertrophy or impairment of micturition have an increased risk of developing acute retention. A marked fall in blood pressure may be seen when ACE inhibitors are added to Frudema therapy. The toxic effects of nephrotoxic antibiotics may be increased by concomitant administration of potent diuretics such Frudema.
OverdoseEffects
- The clinical picture in acute or chronic overdose depends primarily on the extent and consequences of electrolyte and fluid loss, e.g. hypovolaemia, dehydration, haemoconcentration, and cardiac arrhythmias. No specific antidote to Frudema is known. If ingestion has only just taken place, attempts may be made to limit further systemic absorption of the active ingredient by measures such as gastric lavage or those designed to reduce absorption.
TherapeuticClass
- Loop diuretics
StorageConditions
- Protect from light, do not use it later than the date of expiry, and keep all medicines out of the reach of children. To be dispensed only on the prescription of a registered physician.