Ketromin 60 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 95.00 (1 x 5: ৳ 475.00)

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Pacific pharmaceuticals ltd
Also available as
Ketromin 10 mg tablet Ketromin 05 eye drop Ketromin 30 mg injection

Indications

  • short-term management of moderate to severe acute post-operative pain
  • relieve pain, inflammation, and light sensitivity after ocular surgery
  • decrease eye inflammation or redness caused by seasonal allergies

Description

  • Pyrrolo-pyrrole group of NSAID
  • Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits prostaglandins synthesis
  • Metabolized in the liver
  • Highly protein bound

Pharmacology

  • Potent analgesic
  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet recommended dose: 10 mg every 4-6 hours
  • Injection recommended dose: 30 mg every 6 hours for patients <65 years of age
  • Eye Drops: 1 drop in each eye 4 times daily

Interaction

  • Increased side effects with other NSAIDs or aspirin
  • Enhanced anticoagulant effect with anticoagulants
  • Reduced anti-hypertensive effect with Beta Blockers

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Not to be used in children under 16 years of age
  • Contraindicated as prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastrointestinal bleeding
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Hypertension
  • Pulmonary edema

Pregnancy & Lactation

  • US FDA Pregnancy category: C
  • Avoided unless benefits outweigh risks to fetus

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • Discontinue use if corneal epithelial breakdown is observed
  • Not to be used while wearing contact lenses

Therapeutic Class

  • Rheumatoid Arthritis Drugs
  • Non-Opioid Analgesics

Storage Conditions

  • Store in a dry place away from light and heat
  • Keep out of the reach of children

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