Linadi Plus 2.5 mg+850 mg (Tablet)

Unit Price: ৳ 14.00 (7 x 4: ৳ 392.00)

Strip Price: ৳ 56.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	Pacific pharmaceuticals ltd
Also available as	Linadi plus 25 mg tablet Linadi plus 25 mg tablet

Indications

Improves glycemic control in adults with type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4 enzyme
Stimulates insulin release
Decreases glucagon secretion
Lowers basal and postprandial plasma glucose
Improves insulin sensitivity

Dosage & Administration

Individualized dosage
Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals
Gradual dose escalation
Recommended starting dose based on patient's current treatment

Interaction

Interaction with cationic drugs
Interaction with carbonic anhydrase inhibitors
Interaction with inducers of P-glycoprotein and CYP3A4 enzymes
Impact of drugs affecting glycemic control

Contraindications

Contradicted in renal impairment
Acute or chronic metabolic acidosis
Hypersensitivity to Linagliptin or Metformin Hydrochloride

Side Effects

Common side effects include nasopharyngitis and diarrhea
Increased risk of hypoglycemia with sulfonylureas

Pregnancy & Lactation

Use during pregnancy only if clearly needed
Caution during lactation

Precautions & Warnings

Discontinue in case of lactic acidosis or suspected pancreatitis
Monitoring of Vitamin B12 levels
Possible symptoms and precautions in case of lactic acidosis
Recommendations for alcohol consumption, other medicines, counseling, travel, and emergencies
Potential for hypoglycemia

Overdose Effects

Supportive measures in case of overdose
Dialyzability of Metformin Hydrochloride
Clinical findings with Linagliptin overdose
Potential effects of Metformin Hydrochloride overdose

Therapeutic Class

Combination oral hypoglycemic preparations

Storage Conditions

Store below 30°C, protected from light & moisture
Keep out of the reach of children

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