Lotenate Plus 0.5%+0.3% (Ophthalmic Suspension)

5 ml drop: ৳ 200.00

Medicine Details

Category	Details
Generic	Loteprednol etabonate tobramycin
Company	Pacific pharmaceuticals ltd

Indications

Steroid-responsive inflammatory ocular conditions
Superficial bacterial ocular infection
Allergic conjunctivitis
Acne rosacea
Keratitis
Iritis

Pharmacology

Corticosteroid action
Inhibition of phospholipase A2
Bactericidal activity
Inhibition of protein synthesis

Dosage & Administration

Shake well before use
Apply one drop into the conjunctival sac every 4-6 hours
Increased dosing during initial 24-48 hours

Interaction

Not detected in plasma following topical administration
Expected minimal impact on systemic medicinal products

Contraindications

Viral diseases of the cornea and conjunctiva
Hypersensitivity to ingredients
Hypersensitivity to corticosteroids

Side Effects

Increased intraocular pressure
Burning and stinging upon instillation
Vision disorders
Ocular discomfort
Unspecified eye disorders
Headache

Pregnancy & Lactation

Limited data in pregnant women
Use in pregnancy only if benefits outweigh risks
Caution in lactating mothers

Precautions & Warnings

For ophthalmic use only
Monitor intraocular pressure if used for 10 days or longer
Risk of fungal infections with long-term use
Potential for overgrowth of nonsusceptible organisms
Risk of cross-sensitivity to other aminoglycoside antibiotics

Use in Special Populations

Safety and effectiveness in pediatric patients not established

Therapeutic Class

Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

Store at room temperature
Protect from light
Avoid dropper tip contact with surfaces
Do not use contents after 4 weeks from opening
Protect from freezing

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