Minomal SR 600 mg (Tablet (Sustained Release))
Unit Price: ৳ 3.59 (2 x 10: ৳ 71.81)
Strip Price: ৳ 35.91
Medicine Details
| Category | Details |
|---|---|
| Generic | Aminophylline |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of bronchospasm associated with asthma
- Treatment of bronchospasm associated with emphysema
- Prophylaxis of bronchospasm associated with chronic bronchitis
- Treatment of cardiac asthma in adults
- Treatment of left ventricular or congestive cardiac failure in adults
Pharmacology
- Combination of theophylline and ethylenediamine
- Ethylenediamine increases solubility of theophylline
- Relaxes bronchial smooth muscle
- Increases intracellular cAMP through inhibition of phosphodiesterase
- Adenosine receptor antagonism
- Prostaglandin antagonism
- Effects on intracellular calcium
Dosage
- Oral administration for chronic bronchospasm in adults and children
- Intravenous administration for acute severe bronchospasm in adults and children
- Dosage adjustments for elderly and patients with hepatic impairment
Administration
- Oral tablets should be swallowed whole and not chewed
Contraindications
- Hypersensitivity to xanthines or ethylenediamine
- Active peptic ulcer
Side Effects
- Gastric irritation
- Nausea
- Vomiting
- Diarrhea
- Hematemesis
- Epigastric pain
- Tremor
- Ventricular arrhythmias
- Seizures
- Headache
- Irritability
- Restlessness
- Insomnia
- Twitching
- Convulsion
- Reflex hyperexcitability
- Palpitation
- Tachycardia
- Hypotension
- Circulatory failure
- Flushing
- Albuminuria
- Diuresis
- Hematuria
- Inappropriate ADH syndrome
Pregnancy & Lactation
- Use should be balanced against risk of uncontrolled disease
Precautions & Warnings
- Caution for patients with peptic ulceration
- Caution for patients with hyperthyroidism
- Caution for patients with hypertension
- Caution for patients with cardiac arrhythmias or other cardiovascular disease
- Caution for patients with epilepsy
- Caution for patients with heart failure
- Caution for patients with hepatic dysfunction
- Caution for patients with chronic alcoholism
- Caution for patients with acute febrile illness
- Caution for neonates
- Caution for the elderly
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
- Respiratory stimulants: analeptics
- Theophylline & related drugs