Nepco 150 mg (Capsule)

Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00

Medicine Details

Title

Nepco 150 mg Capsule

Categories

  • Medicine
  • Anticonvulsant
  • Pain Management
  • Neuropathy Treatment
  • Seizure Medication

Description

Nepco 150 mg Capsule is indicated for neuropathic pain, postherpetic neuralgia, partial-onset seizures, fibromyalgia, and neuropathic pain associated with spinal cord injury.

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

Pregabalin is a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and binds with high affinity to the alpha2-delta site in central nervous system tissues.

Dosage

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN) in adults: Maximum recommended dose is 100 mg three times a day (300 mg/day)
  • Postherpetic neuralgia in adults (PHN): Recommended dose is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day)
  • Management of fibromyalgia in adults: Recommended dose is 300 to 450 mg/day
  • Route of administration: Oral route. Pregabalin CR tablet should be administered after an evening meal.
  • Conversion from Pregabalin capsules to Pregabalin CR capsule tablet: Instructions provided
  • Pregabalin tablet total daily dose: Dosed 2 or 3 times daily
  • Pregabalin CR capsule capsule dose: Dosed once a day
  • Dosing adjustment: Instructions provided

Administration

  • Route of administration: Oral route. Can be taken with or without food. Pregabalin CR tablet should be swallowed whole and should not be split, crushed or chewed.

Interaction

  • Drug interaction with medication: Nepco is unlikely to be involved in significant pharmacokinetic drug interactions.
  • Drug interaction with food and others: Not applicable

Contraindications

  • Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components.

Side effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Thinking abnormal
  • Increased weight
  • Increased appetite

Pregnancy and lactation

  • Pregnancy: No adequate and well-controlled studies with pregabalin in pregnant women. Potential risk to a fetus.
  • Lactation: Small amounts of pregabalin detected in the milk of lactating women. Breastfeeding is not recommended during treatment with pregabalin.

Precautions and warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise requiring emergency treatment.
  • Discontinuation in case of hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur with concomitant CNS depressants
  • Impairment of the patient's ability to drive or operate machinery
  • Increased seizure frequency or other adverse reactions if rapidly discontinued
  • Peripheral edema may occur
  • Cautious coadministration with thiazolidinedione antidiabetic agents

Use in special populations

  • Use in children and adolescents: Safety and effectiveness not established for various indications
  • Overdose effects: Symptoms include reduced consciousness, depression/anxiety, and seizures

Drug classes

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage conditions

Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children.

Chemical structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure: Image provided

Common questions

  • What is Nepco 150 mg Capsule?: An anticonvulsant and first-line treatment for neuropathic pain, shingles, seizures and fibromyalgia.
  • How long do I need to use Nepco 150 mg Capsule before I see improvement?: Until improvement is observed.
  • At what frequency do I need to use Nepco 150 mg Capsule?: As prescribed by the doctor.
  • Should I use Nepco 150 mg Capsule empty stomach, before or after food?: After food in prescribed dosage.
  • Storage and disposal instructions: Keep in a cool dry place in original packaging. Should be kept unreachable to children and pets.
  • Does Nepco 150 mg Capsule work the same way for each disease?: Works differently for different diseases.
  • How long do I need to take Nepco 150 mg Capsule?: Duration depends on the condition. Consult the doctor before stopping.
  • Can I take Diazepam and Nepco 150 mg Capsule together?: Yes, they can be used together.
  • Can the use of Nepco 150 mg Capsule cause weight gain?: Yes, it may cause weight gain due to increased hunger.

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