Odatron 4 mg (Tablet)

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Ondansetron
Company Pacific pharmaceuticals ltd
Also available as
Odatron 8 mg tablet Odatron 2 mg injection Odatron 8 mg injection Odatron 4 mg oral solution

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Formulation Type

Oral Soluble Film

Application Method

  • Applied on top of the tongue
  • Dissolves within 20 seconds
  • Swallowed with saliva
  • Does not require water for dissolution or swallowing

Active Ingredient

Ondansetron

Empirical Formula

C18H19N3O

Molecular Weight

293.3

Mode of Action

Selective blocking agent of the serotonin 5-HT3 receptor type

Dosage

  • 8 mg orodispersible tablet
  • 4 mg orodispersible tablet
  • Injection
  • Oral solution

Administration Instructions

  • Tear the pouch carefully along with the edge tear mark
  • Place the film on top of the tongue
  • Do not chew or swallow the film whole
  • Swallow after the film dissolves
  • Wash hands after administration

Pharmacological Interaction

Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes

Contraindications

Hypersensitivity to the drug or any of its components, Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Flushing or warmth sensation
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Bronchospasm
  • Tachycardia
  • Angina
  • Hypokalemia
  • Shortness of breath

Pregnancy & Lactation

No adequate and well-controlled studies in pregnant women, Excreted in the breast milk of rats

Precautions & Warnings

  • Hypersensitivity reactions reported
  • Not a drug that stimulates gastric or intestinal peristalsis
  • Caution in patients following abdominal surgery or with chemotherapy-induced nausea and vomiting

Pediatric Uses

  • Little information available about dosage in pediatric patients 4 years of age or younger
  • No dosage adjustment needed in patients over the age of 65

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Temperature not exceeding 30°C, Dry place, Protect from light and moisture

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