Tramic 500 mg/5 ml (IM/IV Injection)
5 ml ampoule: ৳ 80.00 (1 x 5: ৳ 400.00)
Medicine Details
Category | Details |
---|---|
Generic | Tranexamic acid |
Company | Pacific pharmaceuticals ltd |
Also available as |
Indications
- Prophylaxis and therapy of hemoptysis
- Digestive hemorrhages
- Hemorrhagic syndromes in leukemia
- Cirrhosis and hemophilia
- Thrombocytopenic purpura
- Accidents during thrombolytic therapy and transfusion
Pharmacology
- Preparation of tranexamic acid
- Antifibrinolytic action
- Inhibition of plasminogen activation
- Low acute and chronic toxicity
- Well absorbed by oral route
Dosage & Administration
- Usual dose for adults: 500-1000 mg 3 times daily
- Pediatric dose for prophylaxis
- Pediatric dose for therapeutic purposes
- No reduction in dosage for elderly patients
Interaction
- Incompatibility with solutions containing penicillins
- Antagonism with thrombolytic drugs
- Potential for increased thrombus formation with estrogen-containing drugs
- Avoid direct admixture with whole blood during transfusion
Contraindications
- Known individual hypersensitivity
- Thromboembolic disease
- Arterial and venous thrombosis
- Endocavitary hemorrhages
- Serious kidney failure
Side Effects
- Infrequent sense of fatigue
- Conjunctival irritation
- Nasal blockage
- Itching
- Skin reddening
- Exanthems
- Nausea and diarrhea
Pregnancy & Lactation
- Avoid during known and presumed pregnancy
- Passes into breast milk to a low concentration
Precautions & Warnings
- Use in cases of hyperfibrinolysis
- Prophylactic treatment start 24 hours before operation
- Prolong therapy of hemorrhages
- Reduce doses in hematuria
- Caution in renal and hepatic dysfunction
Therapeutic Class
- Anti-fibrinolytic drugs
- Haemostatic drugs
Storage Conditions
- Store at 15-30°C
- Keep away from light
- Keep out of children's reach
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