Tramic 500 mg/5 ml (IM/IV Injection)

5 ml ampoule: ৳ 80.00 (1 x 5: ৳ 400.00)

Medicine Details

Category Details
Generic Tranexamic acid
Company Pacific pharmaceuticals ltd
Also available as

Indications

  • Prophylaxis and therapy of hemoptysis
  • Digestive hemorrhages
  • Hemorrhagic syndromes in leukemia
  • Cirrhosis and hemophilia
  • Thrombocytopenic purpura
  • Accidents during thrombolytic therapy and transfusion

Pharmacology

  • Preparation of tranexamic acid
  • Antifibrinolytic action
  • Inhibition of plasminogen activation
  • Low acute and chronic toxicity
  • Well absorbed by oral route

Dosage & Administration

  • Usual dose for adults: 500-1000 mg 3 times daily
  • Pediatric dose for prophylaxis
  • Pediatric dose for therapeutic purposes
  • No reduction in dosage for elderly patients

Interaction

  • Incompatibility with solutions containing penicillins
  • Antagonism with thrombolytic drugs
  • Potential for increased thrombus formation with estrogen-containing drugs
  • Avoid direct admixture with whole blood during transfusion

Contraindications

  • Known individual hypersensitivity
  • Thromboembolic disease
  • Arterial and venous thrombosis
  • Endocavitary hemorrhages
  • Serious kidney failure

Side Effects

  • Infrequent sense of fatigue
  • Conjunctival irritation
  • Nasal blockage
  • Itching
  • Skin reddening
  • Exanthems
  • Nausea and diarrhea

Pregnancy & Lactation

  • Avoid during known and presumed pregnancy
  • Passes into breast milk to a low concentration

Precautions & Warnings

  • Use in cases of hyperfibrinolysis
  • Prophylactic treatment start 24 hours before operation
  • Prolong therapy of hemorrhages
  • Reduce doses in hematuria
  • Caution in renal and hepatic dysfunction

Therapeutic Class

  • Anti-fibrinolytic drugs
  • Haemostatic drugs

Storage Conditions

  • Store at 15-30°C
  • Keep away from light
  • Keep out of children's reach

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