M-Dazole 200 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 25.67

Medicine Details

Category Details
Generic Metronidazole
Company Modern pharmaceuticals ltd
Also available as
M dazole 200 mg tablet M dazole 400 mg tablet

Title

  • M-Dazole 200 mg/5 ml Suspension

Categories

  • Medicine
  • Antibiotic

Description

  • M-Dazole is indicated in the treatment of various diseases such as prevention of post-operative infections, septicaemia, bacteraemia, trichomoniasis, bacterial vaginosis, amoebiasis, giardiasis, gingivitis, anaerobic leg ulcers, pressure sores, acute dental infections, antibiotic-associated pseudomembranus colitis, etc.
  • Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically. Studies have demonstrated that the reduced form of this drug interacts with DNA and gives bactericidal action of Metronidazole.
  • The recommended dosage and administration vary for different diseases and age groups, including trichomoniasis, intestinal amoebiasis, extra-intestinal & asymptomatic amoebiasis, giardiasis, acute ulcerative gingivitis, bacterial vaginosis, leg ulcers and pressure sores, anaerobic infections, surgical prophylaxis, vaginal gel, suppository, and IV infusion.
  • Interaction with other drugs includes Disulfiram, Alcohol, Oral anticoagulant therapy, Lithium, Cyclosporin, Phenytoin or phenobarbital, 5-Fluorouracil, and Busulfan.
  • Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives.
  • Side effects may include metallic taste, nausea, vomiting, diarrhea, drowsiness, and rashes.
  • Pregnancy Category of Metronidazole is B. Caution should be exercised when administered to a nursing woman.
  • Precautions and warnings include regular hematological tests, caution in patients with hepatic encephalopathy, and warnings about darkening urine.
  • Special precautions for Hepatic impairment and Renal impairment, and overdose effects may include vomiting, ataxia, and slight disorientation.
  • The therapeutic class of M-Dazole is Amoebicides, Anti-diarrhoeal Antiprotozoal.
  • Storage Conditions: Store below 30°C, protected from light, and out of the reach of children.
  • Common Questions include the uses, side effects, duration of improvement, contraindications, safety during pregnancy, and recommendations for the safe use of M-Dazole 200 mg/5 ml Suspension.

DosageAndAdministration

  • The dosage and administration instructions for various diseases and age groups including trichomoniasis, intestinal amoebiasis, extra-intestinal & asymptomatic amoebiasis, giardiasis, acute ulcerative gingivitis, bacterial vaginosis, leg ulcers and pressure sores, anaerobic infections, surgical prophylaxis, vaginal gel, suppository, and IV infusion.

Pharmacology

  • Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically. Studies have demonstrated that the reduced form of this drug interacts with DNA and gives bactericidal action of Metronidazole.

Interaction

  • Disulfiram
  • Alcohol
  • Oral anticoagulant therapy
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives

SideEffects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhea
  • Drowsiness
  • Rashes

PregnancyAndLactation

  • Pregnancy Category B
  • Use during pregnancy only if clearly needed. Excreted in human milk, caution in nursing women.

PrecautionsAndWarnings

  • Regular hematological tests
  • Caution in patients with hepatic encephalopathy
  • Warnings about darkening urine

SpecialPopulations

  • Hepatic impairment
  • Renal impairment

OverdoseEffects

  • Symptoms of vomiting, ataxia, and slight disorientation
  • No specific antidote for M-Dazole overdosages

StorageConditions

  • Store below 30°C
  • Protected from light
  • Keep out of the reach of children

CommonQuestions

  • Uses of M-Dazole 200 mg/5 ml Suspension
  • Side effects of M-Dazole 200 mg/5 ml Suspension
  • Duration of improvement
  • Contraindications to M-Dazole 200 mg/5 ml Suspension
  • Safety during pregnancy
  • Effectiveness when taken in more than the recommended dose

AdditionalInfo

  • Amoebicides
  • Anti-diarrhoeal Antiprotozoal

Indications

  • Prevention of post-operative infections
  • Septicaemia
  • Bacteraemia
  • Trichomoniasis
  • Bacterial vaginosis
  • Amoebiasis
  • Giardiasis
  • Acute ulcerative gingivitis
  • Anaerobically infected leg ulcers
  • Pressure sores
  • Acute dental infections
  • Antibiotic-associated pseudomembranus colitis

Class

  • Antibiotic medication

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