Gembine 200 mg/vial (IV Infusion)

200 mg vial: ৳ 1,600.00

Medicine Details

Category Details
Generic Gemcitabine
Company Healthcare pharmaceuticals ltd
Also available as
Gemzar 200 mg injection Gemzar 1 gm injection Gembine 1 gm injection

Indications

  • Non-Small Cell Lung Cancer
  • Pancreatic Cancer
  • Bladder Cancer
  • Breast Cancer
  • Ovarian Cancer

Dosage & Administration

  • Treatment of Non-Small Cell Lung Cancer
  • Treatment of Pancreatic Cancer
  • Treatment of Bladder Cancer
  • Treatment of Breast Cancer
  • Treatment of Ovarian Cancer

Pharmacology

  • Metabolism by nucleoside kinases
  • Inhibition of DNA synthesis
  • Competes with dCTP for incorporation into DNA
  • Induces apoptosis
  • Self-potentiation of dFdCTP into DNA

Interaction

  • No confirmed interactions reported
  • No specific drug interaction studies conducted

Contraindications

  • Known hypersensitivity to Gemcitabine or any other components of this product

Side Effects

  • Haematological Toxicity
  • Hepatic Toxicity
  • Gastrointestinal effects
  • Genito-Urinary Toxicity
  • Pulmonary Toxicity
  • Allergic Toxicity
  • Neurotoxicity
  • Alopecia

Pregnancy & Lactation

  • Pregnancy Category D
  • Use during pregnancy
  • Unknown excretion in human breast milk

Precautions & Warnings

  • Caution in patients with specific risks
  • Caution in patients with impaired renal function or hepatic insufficiency
  • Caution in children

Use in Special Populations

  • Elderly Patients
  • Renal and Hepatic Impairment
  • Children
  • Directed by registered physicians

Overdose Effects

  • No known antidote
  • Myelosuppression
  • Paresthesias
  • Severe rash
  • Supportive therapy

Therapeutic Class

  • Cytotoxic Chemotherapy

Storage Conditions

  • Store vial in original carton at 20° to 25°C
  • Away from light
  • Do not refrigerate
  • Keep out of the reach of children

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