Gembine 1 gm/vial (IV Infusion)

1 gm vial: ৳ 5,500.00

Medicine Details

Category Details
Generic Gemcitabine
Company Healthcare pharmaceuticals ltd
Also available as
Gemzar 200 mg injection Gemzar 1 gm injection Gembine 200 mg injection

Indications

  • Non-Small Cell Lung Cancer
  • Pancreatic Cancer
  • Bladder Cancer
  • Breast Cancer
  • Ovarian Cancer

Pharmacology

  • Metabolism by nucleoside kinases
  • Inhibition of DNA synthesis
  • Inhibition of ribonucleotide reductase
  • Competes with dCTP for DNA incorporation
  • Induction of apoptosis

Dosage & Administration

  • Dosing regimens for different cancers
  • Intravenous infusion instructions
  • Recommended doses based on cancer type
  • Dosage reduction with toxicity

Interaction

  • No confirmed drug interactions reported
  • No specific drug interaction studies conducted

Contraindications

  • Hypersensitivity to Gemcitabine

Side Effects

  • Haematological Toxicity
  • Hepatic Toxicity
  • Gastrointestinal toxicity
  • Genito-Urinary Toxicity
  • Pulmonary Toxicity
  • Allergic Toxicity
  • Neurotoxicity
  • Alopecia

Pregnancy & Lactation

  • Pregnancy Category D
  • Unknown excretion in human breast milk

Precautions & Warnings

  • Caution in patients with specific risks
  • Schedule-dependent Toxicity
  • Myelosuppression
  • Pulmonary Toxicity
  • Respiratory Failure
  • Hemolytic Uremic Syndrome
  • Embryofetal Toxicity
  • Radiation Therapy Toxicity
  • Impairment of Fertility

Use in Special Populations

  • Elderly Patients
  • Renal and Hepatic Impairment
  • Children

Overdose Effects

  • No known antidote for overdoses
  • Principal toxicities of overdose

Therapeutic Class

  • Cytotoxic Chemotherapy

Storage Conditions

  • Temperature and light-sensitive storage
  • Avoid refrigeration
  • Keep out of the reach of children

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