Idiopag 25 mg (Tablet)

Unit Price: ৳ 600.00 (1 x 7: ৳ 4,200.00)
Strip Price: ৳ 4,200.00

Medicine Details

Indications

  • Treatment of thrombocytopenia in patients with immune thrombocytopenia
  • Treatment of thrombocytopenia in patients with hepatitis C infection
  • Treatment of severe aplastic anemia

Pharmacology

  • Small molecule thrombopoietin (TPO) receptor agonist
  • Interacts with the transmembrane domain of the human TPO-receptor
  • Induces signaling cascades leading to increased platelet production

Dosage & Administration

  • Route of administration: Oral intake
  • Can be taken without a meal or with a meal low in calcium
  • Dosage for different conditions and patient demographics

Interaction

  • Take eltrombopag at least 2 hours before or 4 hours after medications or products containing polyvalent cations
  • Take eltrombopag at least 2 hours before or 4 hours after calcium-rich foods

Contraindications

  • Contraindicated in patients with known hypersensitivity to eltrombopag or any components

Side Effects

  • Common side effects: anemia, nausea, pyrexia, ALT increased, cough, fatigue, headache, diarrhea

Pregnancy & Lactation

  • Insufficient data for assessing drug-associated risks for major birth defects or adverse outcomes
  • Not recommended during breastfeeding

Precautions & Warnings

  • Increased risk of hepatic decompensation in chronic hepatitis C patients
  • Increased risk of progression of myelodysplastic syndromes to acute myeloid leukemia
  • Risk of portal vein thrombosis in patients with chronic liver disease

Use in Special Populations

  • Safety and efficacy not established in pediatric patients below the age of 1 year

Overdose Effects

  • Excessive increase in platelet counts may result in thrombotic complications
  • Consider oral administration of metal cation preparations to limit absorption in case of overdose

Therapeutic Class

  • Haemostatic drugs

Storage Conditions

  • Store in a cool and dry place below 25°C
  • Protect from light
  • Keep away from the reach of children

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