Hi-D 2000 IU (Tablet)
Unit Price: ৳ 2.50 (3 x 10: ৳ 75.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of rickets
- Treatment of osteomalacia
- Immune system support
- Prevention of osteoporosis
- Supports healthy bone and teeth
- Prevention of pre-eclampsia during pregnancy
- Essential nutrient for growing infants
Pharmacology
- Active form is Calcitriol
- Binds to Vitamin D receptors
- Half life of about 50 days
- Absorbed in the small intestine
- Metabolized to 25-hydroxy Vitamin D3 in the liver
- Second hydroxylation occurs in the kidney
- Increases calcium absorption
Dosage & Administration
- 40000 IU once weekly for 7 weeks for adults with Vitamin D3 deficiency
- 1400-2000 IU/day for maintenance therapy in adults
- 20000 IU every 4 weeks for prevention of Vitamin D3 deficiency in adults
- 20000 IU once a month as addition to specific therapy for osteoporosis in adults
- 20000 IU once every 2 weeks for 6 weeks for children with Vitamin D3 deficiency
- 20000 IU every 6 weeks for prevention of Vitamin D3 deficiency in children
- 1000 IU (1-2 tablets) daily for film-coated tablet
- 1000-2000 IU daily for oroflash or chewable tablets
- 400 IU/day for patients with risk of Cholecalciferol deficiency (0-1 yr)
- 600 IU/day for patients with risk of Cholecalciferol deficiency (>1 yr)
- 100000-200000 IU every 6 months for specific populations via injection
- 1 ampoule (1 ml) i.e. 200000 IU for Vitamin D deficiency in adults via injection
Interaction
- Interference with absorption and metabolism by various drugs
- Increased need for Vitamin D3 with Corticosteroids
Contraindications
- Contraindicated in diseases associated with hypercalcemia
- Contraindicated in hypersensitivity to Vitamin D3
- Contraindicated in evidence of Vitamin D3 toxicity
Side Effects
- Anorexia
- Nausea & vomiting
- Diarrhea
- Constipation
- Weight loss
- Polyuria
- Sweating and increased thirst
- Headache
- Vertigo
Pregnancy & Lactation
- Safe use up to 4000 IU during pregnancy
- Excreted in breast milk
- Consideration of dosage in breastfeeding mothers
Precautions & Warnings
- Monitoring plasma-calcium concentration
- Consultation needed for patients with specific conditions
- Consultation needed for users of Digoxin and Thiazide Diuretics
Use in Special Populations
- Safety & efficacy not established in children under 12 years
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children