Hi-D 2000 IU (Tablet)

Unit Price: ৳ 2.50 (3 x 10: ৳ 75.00)
Strip Price: ৳ 25.00

Medicine Details

Category Details
Generic Cholecalciferol vitamin d3
Company Popular pharmaceuticals ltd
Also available as
Hi d 20000 iu capsule Hi d 40000 iu capsule Hi d 200000 iu injectable solution oral im

Indications

  • Prevention of rickets
  • Treatment of osteomalacia
  • Immune system support
  • Prevention of osteoporosis
  • Supports healthy bone and teeth
  • Prevention of pre-eclampsia during pregnancy
  • Essential nutrient for growing infants

Pharmacology

  • Active form is Calcitriol
  • Binds to Vitamin D receptors
  • Half life of about 50 days
  • Absorbed in the small intestine
  • Metabolized to 25-hydroxy Vitamin D3 in the liver
  • Second hydroxylation occurs in the kidney
  • Increases calcium absorption

Dosage & Administration

  • 40000 IU once weekly for 7 weeks for adults with Vitamin D3 deficiency
  • 1400-2000 IU/day for maintenance therapy in adults
  • 20000 IU every 4 weeks for prevention of Vitamin D3 deficiency in adults
  • 20000 IU once a month as addition to specific therapy for osteoporosis in adults
  • 20000 IU once every 2 weeks for 6 weeks for children with Vitamin D3 deficiency
  • 20000 IU every 6 weeks for prevention of Vitamin D3 deficiency in children
  • 1000 IU (1-2 tablets) daily for film-coated tablet
  • 1000-2000 IU daily for oroflash or chewable tablets
  • 400 IU/day for patients with risk of Cholecalciferol deficiency (0-1 yr)
  • 600 IU/day for patients with risk of Cholecalciferol deficiency (>1 yr)
  • 100000-200000 IU every 6 months for specific populations via injection
  • 1 ampoule (1 ml) i.e. 200000 IU for Vitamin D deficiency in adults via injection

Interaction

  • Interference with absorption and metabolism by various drugs
  • Increased need for Vitamin D3 with Corticosteroids

Contraindications

  • Contraindicated in diseases associated with hypercalcemia
  • Contraindicated in hypersensitivity to Vitamin D3
  • Contraindicated in evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating and increased thirst
  • Headache
  • Vertigo

Pregnancy & Lactation

  • Safe use up to 4000 IU during pregnancy
  • Excreted in breast milk
  • Consideration of dosage in breastfeeding mothers

Precautions & Warnings

  • Monitoring plasma-calcium concentration
  • Consultation needed for patients with specific conditions
  • Consultation needed for users of Digoxin and Thiazide Diuretics

Use in Special Populations

  • Safety & efficacy not established in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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