Linastar M 2.5 mg+500 mg (Tablet)

Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)

Strip Price: ৳ 130.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	Orion pharma ltd
Also available as	Linastar m 25 mg tablet

Indications

Adjunct to diet and exercise for type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4 enzyme
Stimulates insulin release
Decreases glucagon secretion
Oral antihyperglycemic drug
Lowers plasma glucose
Improves insulin sensitivity
Decreases hepatic glucose production

Dosage & Administration

Individualized dosage
Maximum recommended dose
Gradual dose escalation
Immediate release tablet
Extended release tablet
Recommended starting dose

Interactions

Cationic drugs interaction
Carbonic anhydrase inhibitors interaction
Inducers of P-glycoprotein and CYP3A4 enzymes interaction
Drugs affecting glycemic control interaction

Contraindications

Renal impairment contraindication
Metabolic acidosis contraindication
Hypersensitivity contraindication

Side Effects

Nasopharyngitis
Diarrhea
Hypoglycemia

Pregnancy & Lactation

Caution during pregnancy
Caution during lactation

Precautions & Warnings

Discontinue in case of lactic acidosis
Discontinue in case of suspected pancreatitis
Discontinue before radiologic studies or surgical procedures
Monitoring of vitamin B12 levels
Symptoms of lactic acidosis
Precautions for alcohol consumption
Precautions for other medicines
Precautions for travel
Precautions in case of emergency
Hypoglycemia symptoms

Overdose Effects

Supportive measures in case of overdose
Removal of unabsorbed material from gastrointestinal tract
Clinical monitoring
Supportive treatment
No dose-related clinical adverse drug reactions
Reports of hypoglycemia and lactic acidosis in overdose cases

Therapeutic Class

Combination oral hypoglycemic preparations

Storage Conditions

Keep in cool & dry place
Below 30°C
Protected from light & moisture
Keep out of the reach of children

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