Doxibac 100 mg (Capsule)
Unit Price: ৳ 2.50 (3 x 10: ৳ 75.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Popular pharmaceuticals ltd |
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Description
- Highly active broad-spectrum antibiotic
- Effective against Gram-positive and Gram-negative bacteria
- Mechanism of action on protein synthesis
Pharmacology
- Bacteriostatic antibiotic
- Active against Staphylococcus aureus and Nocardia
- Active against penicillin-resistant strains
- Sensitivity to various anaerobes
- Active against Haemophilus influenzae and H. ducreyi
- Activity against Nocardia, Chlamydia, Mycoplasma and Rickettsiae
- Active against spirochetes
- Active against Plasmodium falciparum
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Impaired absorption by antacids and iron-containing preparations
- Decrease in half-life by barbiturates, carbamazepine and phenytoin
- Reduced effectiveness of oral contraceptives
- Required downward adjustment of anticoagulant dosages
- Should be avoided in conjunction with penicillin
Contraindications
- Hypersensitivity to tetracyclines
- Children under 8 years of age
- Pregnant women and lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy & Lactation
- Avoided in pregnant women
- Risk of staining and effect on bone growth in the fetus
- Enters breast milk
Precautions & Warnings
- Avoided during tooth development
- May cause permanent discoloration of teeth
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place
- Protected from light