Emirest 4 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 44.00

Medicine Details

Category Details
Generic Ondansetron
Company Pharmasia limited
Also available as

Title

  • Emirest Oral Soluble Film

Categories

  • Medicine
  • Healthcare
  • Pharmaceuticals

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Dosage

  • 8 mg tablet/orodispersible tablet
  • 4 mg orodispersible tablet
  • Injection
  • Ondansetron Oral Solution
  • Ondansetron Oral Solution administered 30 minutes before start of emetogenic chemotherapy

Administration

  • Tear the pouch carefully along with the edge tear mark
  • Put the Ondansetron film on top of your tongue
  • Dissolves within 20 seconds
  • Do not chew or swallow the film whole
  • Swallow after the Onsaf oral soluble film dissolves
  • Wash your hands after taking Onsaf oral soluble film

Interaction

  • Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
  • Inducers or inhibitors of these enzymes may change the clearance and half-life of Emirest

Contraindications

  • Hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Brochospasm
  • Tachycardia
  • Angina
  • Hypokalemia
  • Shortness of breath
  • No evidence of extrapyramidal reactions

Pregnancy & Lactation

  • Carcinogenic effects not seen in rats and mice
  • Ondansetron not mutagenic in standard tests
  • No evidence of impaired fertility or harm to the fetus in rats and rabbits
  • Ondansetron excreted in the breast milk of rats
  • Caution for nursing women

Precautions & Warnings

  • Hypersensitivity reactions reported in patients with hypersensitivity to other selective 5-HT3 receptor antagonists
  • Emirest not a drug that stimulates gastric or intestinal peristalsis
  • Should not be used instead of nasogastric suction
  • Use in patients following abdominal surgery or with chemotherapy-induced nausea and vomiting may mask a progressive ileus and/or gastric distension

Use in Special Populations

  • Dosage recommendation the same for patients with impaired renal function
  • In severe hepatic impairment, a single maximal daily dose of 8 mg recommended
  • Little information available about dosage in pediatric patients 4 years of age or younger
  • No dosage adjustment needed in patients over the age of 65

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store at temperature not exceeding 30°C in a dry place
  • Protect from light and moisture

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