Deformin 500 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Zenith pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Used in adults, children from 10 years of age, and adolescents
- May be used as monotherapy or in combination with other oral antidiabetic agents or with insulin
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers both basal and postprandial plasma glucose
- Decreases hepatic glucose production
Dosage & Administration
- Available in immediate release tablet and extended release tablet forms
- Dosage individualized based on effectiveness and tolerance
- Maximum recommended daily doses should not be exceeded
- Dosage increases should be made in increments
Interaction
- May interact with Furosemide and Nifedipine
- Potential interaction with cationic drugs eliminated by renal tubular secretion
- Certain drugs may produce hyperglycemia and affect glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Acute or chronic diseases causing tissue hypoxia
- Acute alcohol intoxication
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Use of metformin not recommended in pregnancy
- Metformin excreted into human breast milk
- Breastfeeding not recommended during metformin treatment
Precautions & Warnings
- Substantially excreted by the kidney
- May lower vitamin B12 levels
- Increased risk of hypoglycemia when used in combination with insulin
- Regular monitoring of renal function advised
Use in Special Populations
- Dosage adjustments for elderly subjects based on renal function
- Effect on growth and puberty in children to be carefully monitored
Overdose Effects
- Hypoglycemia not seen with doses up to 85 gm
- Lactic acidosis is a medical emergency
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children