Deformin 850 mg (Tablet)

Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Zenith pharmaceuticals ltd
Also available as
Deformin 500 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus
  • Monotherapy for adults
  • Combination therapy for adults
  • Combination therapy for children and adolescents

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers both basal and postprandial plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Maximum recommended daily doses
  • Dosage increases in increments
  • Dosage adjustments for renal impaired patients

Interaction

  • Interaction with Furosemide
  • Enhancement of absorption by Nifedipine
  • Potential interactions with cationic drugs
  • Drugs causing hyperglycemia

Contraindications

  • Hypersensitivity to the active substance
  • Acute metabolic acidosis contraindication
  • Severe renal failure contraindication
  • Acute conditions altering renal function contraindication

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease of vitamin B12 absorption
  • Peripheral neuropathy
  • Taste disturbance
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Recommendation to use insulin during pregnancy
  • Excretion into human breast milk
  • Limited data on breastfeeding

Precautions & Warnings

  • Risk of Deformin accumulation and lactic acidosis
  • Lowering of vitamin B12 levels
  • Increased risk of hypoglycemia
  • Regular monitoring of renal function

Use in Special Populations

  • Dosage adjustment for elderly subjects
  • Confirmation of type 2 diabetes mellitus in children
  • Effect on growth and puberty
  • Caution in prescribing to children aged 10-12 years

Overdose Effects

  • Hypoglycemia absence
  • Lactic acidosis occurrence
  • Treatment with hemodialysis

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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