Etoricoxib 120 mg (Tablet)

Unit Price: ৳ 13.00 (2 x 10: ৳ 260.00)
Strip Price: ৳ 130.00

Medicine Details

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Symptomatic relief of Rheumatoid arthritis (RA)
  • Symptomatic relief of Ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis pain and signs of inflammation
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active COX-2 specific inhibitor
  • Inhibition of COX-2 decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation

Dosage & Administration

  • Recommended dose for Osteoarthritis: 30 mg once daily or 60 mg for insufficient relief
  • Recommended dose for Rheumatoid arthritis: 90 mg once daily
  • Recommended dose for Ankylosing spondylitis: 90 mg once daily
  • Recommended dose for Acute gouty arthritis: 120 mg once daily for 8 days
  • Recommended dose for Postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days
  • Shortest duration possible and the lowest effective daily dose should be used to minimize cardiovascular risks

Interaction

  • Interacts with Oral anticoagulants, Diuretics, ACE inhibitors, Angiotensin II Antagonists, Acetylsalicylic Acid, Ciclosporin, tacrolimus, and Lithium
  • Take without regards to meals

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active GI bleeding
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Pregnancy, lactation, and children under 16 years of age
  • Inflammatory bowel disease, Congestive heart failure, Hypertension, Ischaemic heart disease, Peripheral arterial disease, and Cerebrovascular disease

Side Effects

  • Palpitation, fatigue, influenza-like symptoms, ecchymosis
  • Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
  • Atrial fibrillation, transient ischaemic attack, chest pain
  • Flushing, cough, dyspnoea, epistaxis, anxiety
  • Impaired mental acuity, paraesthesia, electrolyte disturbance
  • Myalgia, arthralgia, confusion, hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not known whether excreted in human milk - not recommended for breastfeeding women

Precautions & Warnings

  • Caution with patients at risk of developing GI complications with NSAIDs
  • Caution with patients at risk of cardiovascular events
  • Monitoring of renal function in certain patients
  • Exercise caution in patients with cardiac failure, edema, liver dysfunction, and signs of hypersensitivity
  • May mask fever and other signs of inflammation
  • Consideration needed when co-administering with warfarin or other oral anticoagulants

Overdose Effects

  • No significant toxicity observed with single or multiple doses up to 150 mg/day
  • Usual supportive measures to be employed in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C, protect from light and moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions

  • Duration of effect, onset of action, pregnancy warnings, habit-forming tendencies, breast-feeding warnings, safety with alcohol, safety to drive, effect on kidney and liver function, quick tips for usage

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