Etoricoxib 60 mg (Tablet)
Unit Price: ৳ 6.00 (4 x 10: ৳ 240.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Zenith pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Symptomatic relief of Rheumatoid arthritis (RA)
- Symptomatic relief of Ankylosing spondylitis
- Symptomatic relief of acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 decreases clinical signs and symptoms
- Decreased potential for GI toxicity and effects on platelet aggregation
Dosage & Administration
- 30 mg once daily for Osteoarthritis
- 90 mg once daily for Rheumatoid arthritis and Ankylosing spondylitis
- 120 mg once daily for acute gouty arthritis
- 90 mg once daily for postoperative dental surgery pain
- Shortest duration possible and lowest effective daily dose should be used
Interaction
- Oral anticoagulants may increase prothrombin time
- NSAIDs may reduce the effect of diuretics and other antihypertensive drugs
- Can be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis
- Potential interaction with ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active GI bleeding
- Patients with allergy or bronchospasm to NSAIDs
- Pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, and others
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transiet ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Anxiety
- Mental acuity impaired
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Not known whether excreted in human milk
- Excreted in the milk of lactating rats
- Breastfeeding must be avoided
Precautions & Warnings
- Caution with elderly and patients using other NSAIDs or acetylsalicylic acid
- Caution with significant risk factors for cardiovascular events
- Monitoring of renal function should be considered
- Caution in patients with cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function should be considered
- Discontinue at first appearance of hypersensitivity
- May mask fever and other signs of inflammation
- Exercise caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
- Usual supportive measures should be employed in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store at a temperature of below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Etoricoxib 60 mg Tablet
- Selective COX-2 inhibitor for pain relief
- Duration of effect lasts for an average duration of 20-24 hours
- Onset of action can be observed within 1-2 hours of administration
- Not recommended for pregnant or breastfeeding women
- Not habit forming
- Unsafe to consume with alcohol
- May affect alertness and kidney/liver function
- Various precautions and quick tips for usage