Etoricoxib 90 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
Category | Details |
---|---|
Generic | Etoricoxib |
Company | Zenith pharmaceuticals ltd |
Also available as |
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Moderate pain associated with dental surgery
Pharmacology
- Potent cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 decreases clinical signs and symptoms
- Selective inhibition of COX-2 decreases potential for GI toxicity and effects on platelet aggregation
- Dose-dependent inhibition of COX-2 without inhibition of COX-1
Dosage & Administration
- Recommended doses for different conditions
- Patients may require additional postoperative analgesia
- Shortest duration possible and lowest effective daily dose should be used
- Patient's need for symptomatic relief and response to therapy should be re-evaluated periodically
Interaction
- Interaction with oral anticoagulants, diuretics, ACE inhibitors, angiotensin II antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, lithium
- Take without regards to meals
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Active peptic ulceration or active GI bleeding
- Patients with specific allergic-type reactions
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Hypertension
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excreted in the milk of lactating rats
- Women who use the product must not breastfeed
Precautions & Warnings
- Caution with patients at risk of developing gastrointestinal complication with NSAIDs
- Patients with significant risk factors for cardiovascular events should be treated with caution
- Monitoring of renal function should be considered
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, hypertension, pre-existing edema
- Monitoring of liver function and discontinuation if signs of hepatic insufficiency occur
- Discontinue in case of hypersensitivity, and caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- Administration of single and multiple doses did not result in significant toxicity
- Usual supportive measures in the event of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store at a temperature of below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula : C18H15ClN2O2S
Common Questions about Etoricoxib 90 mg Tablet
- Uses
- Duration of effect
- Onset of action
- Pregnancy warnings
- Habit forming tendencies
- Breast-feeding warnings
- Safety with alcohol
- Safety to drive while on this medicine
- Effect on kidney function
- Effect on liver function
- Quick tips