Diafit 850 mg (Tablet)
Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Team pharmaceuticals ltd |
| Also available as |
Title
- Diafit Tablet
Categories
- Medicine
- Diabetes Management
- Oral Antidiabetic Drug
- Therapeutic Drug
Description
- Diafit tablets are used for the treatment of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone do not result in adequate glycaemic control.
Formulation
- Immediate Release Tablet
- Extended Release Tablet
Active Ingredient
- Metformin Hydrochloride
Pharmacological Class
- Biguanides
Indications
- Treatment of type 2 diabetes mellitus in adults and children from 10 years of age
- Reduction of diabetic complications in overweight type 2 diabetic adult patients treated with metformin as first-line therapy after diet failure
Mode of Action
- Lowers both basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Decreases intestinal absorption of glucose
- Improves insulin sensitivity by increasing peripheral glucose uptake and utilization
Dosage and Administration
- Dosage must be individualized based on effectiveness and tolerance
- Dosage increments of 500 mg weekly or 850 mg every 2 weeks
- Maximum daily doses for adults and children
- Dosage adjustments for renal-impaired patients
- Instructions for immediate and extended release tablets
Interactions
- Potential interactions with Furosemide, Nifedipine, cationic drugs, and certain medications that produce hyperglycemia
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function or causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Taste disturbance
- Gastrointestinal disorders
- Hepatic function test abnormalities
- Skin reactions
Pregnancy and Lactation
- Increased risk of congenital abnormalities and perinatal mortality with uncontrolled diabetes during pregnancy
- Excretion into human breast milk
Precautions and Warnings
- Substantial excretion by the kidney
- Decreased vitamin B12 levels
- Increased risk of hypoglycemia when used in combination with insulin
- Monitoring of renal function
- Caution in elderly and renal-impaired patients
Use in Special Populations
- Adjustment of metformin dosage in elderly subjects
- Confirmation of type 2 diabetes mellitus before treatment initiation in children
- Regular assessment of renal function
- Caution in situations affecting renal function
Overdose Effects
- Hypoglycemia not seen at normal doses
- Lactic acidosis as a medical emergency
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children