Frusiton 40 mg+50 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Furosemide spironolactone |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Chronic congestive heart failure
- Hepatic cirrhosis with ascites
- Swelling due to excess fluid retention
- Hyperaldosteronism
- Resistant edema associated with secondary hyperaldosteronism
Pharmacology
- Complementary mechanisms of action
- Additive or synergistic diuretic effect
- Inhibition of Na+/K+/2Cl- co-transporter
- Block of reabsorption of sodium, potassium, and chloride ions
Dosage & Administration
- Furosemide 20 and spironolactone 50 mg
- Furosemide 40 and spironolactone 50 mg
- Dosage adjustment based on patient's response
- Use in children not suitable
Interactions
- Increased risk of hyperkalemia with ACE inhibitors
- Increased levels of cardiac glycosides
- Potential interaction with corticosteroids
- Possible reduction of diuretic effects when used with NSAIDs
- Increased ototoxicity with aminoglycoside antibiotics
- Reduced natriuretic effect when used with sucralfate
Contraindications
- Anuria
- Acute renal insufficiency
- Severe impairment of renal function
- Hyperkalemia
- Addison's disease
- Hypersensitivity to Spironolactone, Furosemide, or sulphonamides
Side Effects
- Headache
- Drowsiness
- Gastrointestinal distress
- Ataxia
- Mental confusion
- Gynaecomastia
- Hirsutism
- Deepening of the voice
- Transient increase in blood-urea-nitrogen concentrations
- Hyponatremia
- Hyperkalemia
- Dehydration
- Reduction in blood volume
- Cardiac arrhythmias
Pregnancy & Lactation
- Potential hazards to the fetus
- Alternative method of infant feeding should be considered
- Discontinuation of breast-feeding if treatment is essential
Precautions & Warnings
- Caution in patients liable to electrolyte deficiency
- Use with caution in diabetes, enlarged prostate, hypotension, and hypovolemia
Therapeutic Class
- Potassium-sparing diuretics
- Aldosterone antagonists
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children