Fluconaaf 50 mg (Capsule)
Unit Price: ৳ 7.50 (3 x 10: ৳ 225.00)
Strip Price: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Naafco pharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
Dosage & Administration
- Adult dosage for various conditions
- Child dosage for different weight ranges
- Dosage adjustments for elderly patients and those with renal impairment
- Renal clearance in children
Interactions
- Interaction with warfarin
- Interaction with sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with oral contraceptives
- Interaction with cyclosporin
- Impact of co-administration with food, cimetidine, and antacids
- Impact on theophylline levels
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal side effects
- Rarely encountered rash
- Rare occurrence of anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals at high doses
- Recommendation against use in pregnancy or in women of childbearing potential unless adequate contraception is used
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological and other biochemical function tests in some patients
- Rare cases of hepatic necrosis
- Potential for cutaneous reactions like Stevens Johnson Syndrome
- Caution in patients with rash development
- Not recommended for use during lactation
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Use in the elderly
- Adjustments in patients with renal impairment
- Dosage adjustments based on creatinine clearance levels
Overdose Effects
- Supportive and symptomatic treatment
- Potential for gastric lavage if necessary
- Increased elimination rate with forced volume diuresis
- Effectiveness of haemodialysis in reducing plasma levels
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children