Xevlin 500 mg (Tablet)

Unit Price: ৳ 40.00 (2 x 6: ৳ 480.00)
Strip Price: ৳ 240.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Everest pharmaceuticals ltd
Also available as
Xevlin 200 mg suspension

Title

  • Xevlin 500 mg Tablet

Categories

  • Medicine
  • Antibiotic
  • Macrolide

Description

  • Indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, and skin and soft tissue infections
  • Treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
  • Readily absorbed and greater absorption on an empty stomach
  • Time to peak concentration in adults is 2.1 to 3.2 hours
  • High concentration in phagocytes and actively transported to the site of infection
  • Bacterial protein synthesis interference without affecting nucleic acid synthesis
  • Oral dosage for adults: 500 mg once daily for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days
  • Oral dosage for children: 10 mg/kg body weight once daily for 3 days for child over 6 months
  • Recommended dosage of Azithromycin for injection for adult patients with community-acquired pneumonia
  • Reconstitution procedure of suspension: Shake the bottle well, add boiled and cooled water, shake until powder is completely mixed with water
  • Interaction with antacid, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine
  • Contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic, co-administration of ergot derivatives, and in patients with hepatic diseases
  • Low incidence of side-effects, most observed side-effects were gastrointestinal in origin
  • Pregnancy Category of Azithromycin is B with caution advised for use during pregnancy and lactation
  • Precautions and warnings for rare serious allergic reactions, use in renal and hepatic impairment, and effects on ability to drive and use machines
  • No data on overdosage with Xevlin, typical symptoms of overdosage with macrolide antibiotics, and recommended supportive measures
  • Storage conditions to keep in a dry place away from light and heat, and out of the reach of children
  • Molecular Formula: C38H72N2O12

Pharmacology

  • Azithromycin is acid-stable and can be taken orally with no need of protection from gastric acids
  • Absorption is greater on an empty stomach with a time to peak concentration in adults of 2.1 to 3.2 hours
  • High concentration in phagocytes and actively transported to the site of infection
  • Binding to the 50S ribosomal subunit of susceptible microorganisms interfering with microbial protein synthesis

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