Xevlin 500 mg (Tablet)
Unit Price: ৳ 40.00 (2 x 6: ৳ 480.00)
Strip Price: ৳ 240.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Everest pharmaceuticals ltd |
| Also available as |
Title
- Xevlin 500 mg Tablet
Categories
- Medicine
- Antibiotic
- Macrolide
Description
- Indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, and skin and soft tissue infections
- Treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
- Readily absorbed and greater absorption on an empty stomach
- Time to peak concentration in adults is 2.1 to 3.2 hours
- High concentration in phagocytes and actively transported to the site of infection
- Bacterial protein synthesis interference without affecting nucleic acid synthesis
- Oral dosage for adults: 500 mg once daily for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days
- Oral dosage for children: 10 mg/kg body weight once daily for 3 days for child over 6 months
- Recommended dosage of Azithromycin for injection for adult patients with community-acquired pneumonia
- Reconstitution procedure of suspension: Shake the bottle well, add boiled and cooled water, shake until powder is completely mixed with water
- Interaction with antacid, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine
- Contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic, co-administration of ergot derivatives, and in patients with hepatic diseases
- Low incidence of side-effects, most observed side-effects were gastrointestinal in origin
- Pregnancy Category of Azithromycin is B with caution advised for use during pregnancy and lactation
- Precautions and warnings for rare serious allergic reactions, use in renal and hepatic impairment, and effects on ability to drive and use machines
- No data on overdosage with Xevlin, typical symptoms of overdosage with macrolide antibiotics, and recommended supportive measures
- Storage conditions to keep in a dry place away from light and heat, and out of the reach of children
- Molecular Formula: C38H72N2O12
Pharmacology
- Azithromycin is acid-stable and can be taken orally with no need of protection from gastric acids
- Absorption is greater on an empty stomach with a time to peak concentration in adults of 2.1 to 3.2 hours
- High concentration in phagocytes and actively transported to the site of infection
- Binding to the 50S ribosomal subunit of susceptible microorganisms interfering with microbial protein synthesis