Lacitone 20 mg+50 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Furosemide spironolactone
Company General pharmaceuticals ltd

Indications

  • Essential hypertension
  • Chronic congestive heart failure
  • Hepatic cirrhosis
  • Swelling due to excess fluid retention
  • Hyperaldosteronism
  • Resistant edema associated with secondary hyperaldosteronism

Pharmacology

  • Complementary mechanisms and sites of action
  • Additive or synergistic diuretic effect
  • Inhibition of Na+/K+/2Cl- co-transporter
  • Blockage of reabsorption of sodium, potassium, and chloride ions

Dosage & Administration

  • Dosage range of Furosemide and spironolactone
  • Specific dosage for previously stabilized patients
  • Inappropriateness for use in children
  • Slower excretion in the elderly

Interaction

  • Increased risk of hyperkalemia when taken with ACE inhibitors or potassium salts
  • Enhanced levels of cardiac glycosides in the blood
  • Potential reduction in blood pressure lowering and diuretic effects when used with certain drugs

Contraindications

  • Contraindicated in patients with specific conditions or hypersensitivity to the components

Side Effects

  • Occurrence of various side effects such as headache, drowsiness, gastrointestinal distress, ataxia, mental confusion, skin rashes, gynaecomastia, endocrine disorders, increase in blood-urea-nitrogen concentrations, mild acidosis, hyponatremia, hyperkalemia, excessive diuresis
  • Potential serious depletion of potassium and magnesium leading to cardiac arrhythmias

Pregnancy & Lactation

  • Possible hazards to the mother and fetus during pregnancy
  • Consideration of potential risks to the fetus when using Furosemide in women of childbearing age
  • Detection of metabolites of Spironolactone in breast milk
  • Recommendation to discontinue breastfeeding if Furosemide treatment is essential

Precautions & Warnings

  • Caution in patients liable to electrolyte deficiency, diabetes, enlarged prostate, hypotension, and hypovolemia

Therapeutic Class

  • Belonging to the therapeutic classes of potassium-sparing diuretics and aldosterone antagonists

Storage Conditions

  • Storage below 30°C temperature, away from light and moisture

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