Lasilactone 20 mg+50 mg (Tablet)

Unit Price: ৳ 6.04 (5 x 10: ৳ 302.00)
Strip Price: ৳ 60.40

Medicine Details

Category Details
Generic Furosemide spironolactone
Company Synovia pharma plc

Indications

  • Essential hypertension
  • Chronic congestive heart failure
  • Hepatic cirrhosis
  • Abdominal cavity fluid collection
  • Excess fluid retention swelling
  • Hyperaldosteronism
  • Resistant edema

Pharmacology

  • Complementary mechanisms of action
  • Additive diuretic effects
  • Potassium loss due to Furosemide
  • Inhibition of aldosterone by Spironolactone

Dosage & Administration

  • Furosemide 20 and spironolactone 50 mg tablet
  • Furosemide 40 and spironolactone 50 mg tablet
  • Dosage range for Furosemide and spironolactone
  • Use in children not suitable
  • Slow excretion in the elderly

Interaction

  • Increased risk of hyperkalemia with ACE inhibitors
  • Elevated levels of cardiac glycosides
  • Potential hypokalemia with corticosteroids
  • Reduced diuretic effects when used with NSAIDs
  • Possible ototoxicity of aminoglycoside antibiotics

Contraindications

  • Anuria
  • Acute renal insufficiency
  • Hyperkalaemia
  • Addison's disease
  • Hypersensitivity to Spironolactone or Furosemide

Side Effects

  • Headache and drowsiness
  • Gastrointestinal distress
  • Ataxia and mental confusion
  • Gynaecomastia and breast enlargement
  • Endocrine disorders
  • Increase in blood-urea-nitrogen concentrations
  • Hyponatremia and hyperkalemia
  • Dehydration and reduction in blood volume
  • Serious depletion of potassium and magnesium

Pregnancy & Lactation

  • Placental barrier crossing
  • Potential fetal abnormalities
  • Metabolites in breast milk
  • Discontinuation of breast-feeding if essential

Precautions & Warnings

  • Caution in patients liable to electrolyte deficiency
  • Use with caution in diabetes and hypotension

Therapeutic Class

  • Potassium-sparing diuretics
  • Aldosterone antagonists

Storage Conditions

  • Keep below 30°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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