Favira 200 mg (Tablet)

Unit Price: ৳ 200.00 (1 x 20: ৳ 4,000.00)

Medicine Details

Category Details
Generic Favipiravir
Company Drug international ltd

Indications

  • Treatment of novel or re-emerging pandemic influenza virus infections

Description

  • FDA-approved influenza antiviral drug
  • Selective inhibition of influenza and COVID-19 RNA polymerase
  • Effective in treating COVID-19

Pharmacology

  • Metabolized into favipiravir ribosyl triphosphate
  • Selectively inhibits RNA polymerase of influenza virus
  • Effective against all types and sub-types of human influenza A, B, and C viruses in vitro

Dosage & Administration

  • Usual adult dosage of 1600 mg orally twice daily on Day 1
  • Followed by 600 mg orally twice daily from Day 2 to Day 5
  • Total treatment duration of 5 days

Interaction

  • Animal studies show decreased RBC production
  • Increases in liver function parameters such as AST, ALP, ALT, and total bilirubin
  • Increased vacuolization in hepatocytes

Contraindications

  • Contraindicated for pregnant women and women who may possibly be pregnant

Side Effects

  • Most common side effects are diarrhea and increase of blood uric acid levels

Pregnancy & Lactation

  • May cause delayed development or death of embryos during early pregnancy
  • Should not be given during pregnancy

Precautions & Warnings

  • Should not be given in pregnant women
  • Confirmation of non-pregnancy in women of childbearing potential required before use
  • Thorough contraception measures required from start to 7 days after the end of treatment
  • Caution should be taken for hepatic and renal impaired patients

Use in Special Populations

  • Approved as an experimental drug
  • Further studies needed for efficacy, toxic reactions, and use in children

Overdose Effects

  • Animal studies indicate decreased RBC production
  • Increases in liver function parameters such as AST, ALP, ALT, and total bilirubin
  • Increased vacuolization in hepatocytes
  • Toxicity information in humans not readily available

Therapeutic Class

  • Anti-viral drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

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