Favira 200 mg (Tablet)
Unit Price: ৳ 200.00 (1 x 20: ৳ 4,000.00)
Medicine Details
Category | Details |
---|---|
Generic | Favipiravir |
Company | Drug international ltd |
Indications
- Treatment of novel or re-emerging pandemic influenza virus infections
Description
- FDA-approved influenza antiviral drug
- Selective inhibition of influenza and COVID-19 RNA polymerase
- Effective in treating COVID-19
Pharmacology
- Metabolized into favipiravir ribosyl triphosphate
- Selectively inhibits RNA polymerase of influenza virus
- Effective against all types and sub-types of human influenza A, B, and C viruses in vitro
Dosage & Administration
- Usual adult dosage of 1600 mg orally twice daily on Day 1
- Followed by 600 mg orally twice daily from Day 2 to Day 5
- Total treatment duration of 5 days
Interaction
- Animal studies show decreased RBC production
- Increases in liver function parameters such as AST, ALP, ALT, and total bilirubin
- Increased vacuolization in hepatocytes
Contraindications
- Contraindicated for pregnant women and women who may possibly be pregnant
Side Effects
- Most common side effects are diarrhea and increase of blood uric acid levels
Pregnancy & Lactation
- May cause delayed development or death of embryos during early pregnancy
- Should not be given during pregnancy
Precautions & Warnings
- Should not be given in pregnant women
- Confirmation of non-pregnancy in women of childbearing potential required before use
- Thorough contraception measures required from start to 7 days after the end of treatment
- Caution should be taken for hepatic and renal impaired patients
Use in Special Populations
- Approved as an experimental drug
- Further studies needed for efficacy, toxic reactions, and use in children
Overdose Effects
- Animal studies indicate decreased RBC production
- Increases in liver function parameters such as AST, ALP, ALT, and total bilirubin
- Increased vacuolization in hepatocytes
- Toxicity information in humans not readily available
Therapeutic Class
- Anti-viral drugs
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children