Bexitrol F 50 mcg+100 mcg (Inhaler)

Indications

• Regular treatment of asthma
• Management of diffuse airway obstruction

Pharmacology

• Salmeterol: 12-hour selective long-acting beta-2-adrenoceptor agonist
• Fluticasone Propionate: potent glucocorticoid anti-inflammatory action within the lungs

Dosage

• Adults and adolescents dosing
• Children dosing
• Special patient groups dosing

Administration

• Correct inhaler usage steps
• Cleaning instructions for inhaler

Interaction

• Avoidance of non-selective and selective β-blockers in asthma patients
• Care when co-administering strong CYP3A4 inhibitors

Contraindications

• Hypersensitivity to salmeterol xinafoate, fluticasone propionate
• Primary treatment of status asthmaticus

Side Effects

• Tremor, palpitations, headache (Salmeterol)
• Hoarseness, candidiasis (Fluticasone Propionate)

Pregnancy & Lactation

• Consideration for administration during pregnancy and lactation
• Reproductive toxicity studies in animals

Precautions & Warnings

• Not initiating treatment during an exacerbation
• Possible development of pneumonia in COPD patients
• Systemic effects of inhaled corticosteroids

Use in Special Populations

• Potential reduction in growth velocity in paediatric patients

Overdose Effects

• Signs and symptoms of overdose for both drugs
• Treatment for Salmeterol and Fluticasone Propionate overdose

Therapeutic Class

• Long-acting selective β-adrenoceptor stimulants
• Respiratory corticosteroids

Storage Conditions

• Pressurised canister storage precautions
• Avoiding storage in direct sunlight or heat

Related Brands

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