Bexitrol F 50 mcg+250 mcg (Inhaler)

Indications

• regular treatment of asthma
• combination product (long-acting β2-agonist and inhaled corticosteroid) use

Pharmacology

• Salmeterol Xinafoate as a selective, long-acting beta-2 agonist
• Fluticasone Propionate as a corticosteroid with glucocorticoid activity
• mechanisms of action for both drugs

Dosage

• recommended dosages for adults, adolescents, and children
• dosage variations based on severity and age
• recommended starting dosages for different patient groups
• instructions for using Maxhaler

Administration

• guidelines for using an inhaler effectively
• instructions for cleaning the inhaler

Interaction

• avoidance of non-selective and selective β-blockers
• caution when co-administering strong CYP3A4 inhibitors

Contraindications

• history of hypersensitivity to salmeterol xinafoate, fluticasone propionate, or excipients
• primary treatment of status asthmaticus or acute asthma episodes

Side Effects

• adverse reactions associated with Salmeterol and Fluticasone Propionate
• incidence and types of adverse events

Pregnancy & Lactation

• consideration of administration during pregnancy and lactation
• reproductive toxicity studies in animals
• insufficient human experience data

Precautions & Warnings

• not to initiate during asthma exacerbation
• warning about serious asthma-related adverse events
• potential of paradoxical bronchospasm
• increased reporting of pneumonia in COPD patients
• systemic effects of inhaled corticosteroids

Use in Special Populations

• potential reduction in growth velocity in pediatric patients

Overdose Effects

• signs and symptoms of Salmeterol and Fluticasone Propionate overdose
• treatment for Salmeterol overdose
• effects of acute and chronic overdose

Therapeutic Class

• long-acting selective β-adrenoceptor stimulants
• respiratory corticosteroids

Storage Conditions

• guidelines for storage and handling of pressurized canister

Related Brands

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