Aspasom 5 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 23.00 (2 x 5: ৳ 230.00)

Medicine Details

Category Details
Generic Tiemonium methylsulphate
Company Kemiko pharmaceuticals ltd
Also available as
Aspasom 50 mg tablet Aspasom 10 mg syrup

Indications

  • Reduces muscle spasm of the intestine
  • Reduces muscle spasm of the biliary system
  • Reduces muscle spasm of the bladder
  • Reduces muscle spasm of the uterus
  • Used in symptomatic treatment of pain related to functional disorders of the digestive tract
  • Used in symptomatic treatment of pain related to functional disorders of the biliary system
  • Indicated for the treatment of spasm and pain in urological diseases
  • Indicated for the treatment of spasm and pain in gynaecological diseases

Pharmacology

  • Competitive antagonist of Acetylcholine
  • Competitive antagonist of Histamine
  • Strengthens calcium bond with membrane phospholipids and proteins
  • Inhibits intracellular contractile protein of visceral cells
  • Causes inhibition of visceral spasm and pain

Dosage & Administration

  • Usual adult dose: 2-6 tablets daily in divided doses
  • Usual adult dose: 3-9 teaspoonfuls syrup daily in divided doses
  • Children's dose: 3 ml/kg body weight daily in divided doses
  • Children's dose: 6 mg/kg body weight daily in divided doses
  • Injection dose: 1 Tiemonium Methylsulphate Injection 3 times daily
  • Suppository dose: 20 mg Tiemonium Methylsulphate two or three times daily through rectal route

Interaction

  • Should not be used with other drugs without consulting a physician

Contraindications

  • Not to be used in urethroprostatic disorder involving a risk of urine retention
  • Contraindicated in patients at risk of angle closure glaucoma

Side Effects

  • Risk of hypotension
  • Risk of tachycardia

Pregnancy & Lactation

  • No teratogenic effects reported in animal studies
  • Prudence should be exercised in nursing mothers

Precautions & Warnings

  • Caution should be taken in patients with disorders of the prostate
  • Caution should be taken in case of chronic bronchitis
  • Caution should be taken in case of coronary insufficiency
  • Caution should be taken in case of ambient hyperthermia
  • Caution should be taken in case of renal insufficiency
  • Caution should be taken in case of hepatic insufficiency
  • Risks of visual disturbances
  • May cause danger in driving or using machines

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established
  • Efficacy and safety maintained with increasing age in geriatric patients

Overdose Effects

  • No available data on overdose effects

Therapeutic Class

  • Anticholinergics

Storage Conditions

  • Keep in a dry place
  • Keep away from light and heat
  • Keep out of reach of children

Common Questions about Aspasom 5 mg/2 ml Injection

  • Reduces muscle spasm of the intestine
  • Reduces muscle spasm of the biliary system
  • Reduces muscle spasm of the bladder
  • Reduces muscle spasm of the uterus
  • Used for the treatment of pain in digestive tract and biliary system
  • Indicated for the treatment of spasm and pain in urological diseases
  • Indicated for the treatment of spasm and pain in gynaecological diseases

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