Biotrim (200 mg+40 mg)/5 ml (Oral Suspension)

Indications

• Bactericidal activity against a wide range of organisms
• Suitable for respiratory tract infections
• Effective for genito-urinary tract infections
• Can treat gastrointestinal tract infections
• Broad-spectrum antibiotic

Pharmacology

• Broad spectrum bactericidal activity
• Blocks bacterial enzyme systems
• Contains Trimethoprim and Sulphamethoxazole

Dosage & Administration

• Dosage for mild to severe infections
• Different dosages for different age groups
• Specific dosages for long-term therapy
• Recommended dosage for gonorrhoea

Contraindications

• Hypersensitivity to trimethoprim or sulphonamides
• Not suitable for patients with megaloblastic anaemia
• Avoid in patients with liver or renal damage

Side Effects

• Rare side effects like crystalluria and haemolysis reported
• Less serious side effects include malaise and headache
• Side effects are transient and typically non-withdrawable

Pregnancy & Lactation

• Not recommended during pregnancy or nursing period
• May pass through placenta and breast milk
• Potential risk of kernicterus

Precautions & Warnings

• Prolonged use may lead to macrocytic anaemia
• Interference with Folic acid conversion
• Careful administration in diabetic patients on sulphonylurea drugs

Therapeutic Class

• Belongs to Anti-diarrhoeal Antimicrobial drugs
• Categorized under Sulphonamides & Trimethoprim

Storage Conditions

• Store below 30°C temperature
• Keep away from light and moisture
• Ensure out of reach of children

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