Myocor 5 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
Category | Details |
---|---|
Generic | Bisoprolol hemifumarate |
Company | Biopharma limited |
Also available as |
Title
- Myocor 5 mg Tablet
Categories
- Medicine
- Cardiovascular Health
- Hypertension
- Angina
- Heart Failure
Description
- Myocor is indicated in hypertension, angina, and moderate to severe heart failure.
- Bisoprolol Hemifumarate is the most selective β1 blocker.
- Dosage must be individualized to the needs of the patient.
- Myocor fumarate should not be combined with other β-blocking agents.
- In patients with cardiogenic shock, overt heart failure, second or third degree A-V block, right ventricular failure secondary to pulmonary hypertension and sinus bradycardia.
Dimensions
Color Options
Functions
- Lowers blood pressure
- Reduces heart rate and cardiac output
- Prevents chest pain
- Selectively blocks β1 adrenergic receptor in the heart and vascular smooth muscle
- Reduces arterial hypertension
- Ensures extremely low inter and intra-individual variability of the plasma concentration profiles
Materials
Technical Specifications
- High therapeutic reliability based on pharmacokinetic properties
- Almost completely absorbed from the gastrointestinal tract
- Absolute bioavailability of 88%
- Medium distribution volume is 3.51/kg
- Metabolized via oxidative pathways with no subsequent conjugation
- Renal elimination of the unchanged molecule
- Half-life of 10-12 hours
Design Elements
Usability Features
- Can be taken with or without food
- Appropriate interval for dose titration is 2 weeks
- Safe for use in the elderly
- Safety and effectiveness in children have not been established
- Consideration needed for patients with renal or hepatic impairment
Interaction
- Not recommended to be combined with other β-blocking agents
- Should be used with care when myocardial depressants or inhibitors of A-V conduction are used concurrently
- Combined use with calcium channel blockers can lead to severe hypotension, bradycardia, and cardiac failure
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Dosage & Administration
- Usual starting dose is 5 mg once daily
- Dose titration at 2-week intervals
- Increasing the dose beyond 20 mg once daily yields only a small incremental benefit
- No established safety and effectiveness in children
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Disturbances of the gut
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties
- Bronchospasm in people with asthma or COPD
Pregnancy & Lactation
- Not teratogenic in rats at recommended doses
- Fetotoxic and maternotoxic at higher doses
- No studies in pregnant women
- Small amounts detected in the milk of lactating rats
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
- Mothers should stop nursing if essential use
Precautions & Warnings
- Use caution in adjusting the dose in patients with renal or hepatic impairment
- Patients with a history of severe anaphylactic reaction may be more reactive to repeated challenge
- Unresponsive to usual doses of epinephrine to treat allergic reactions
Therapeutic Class
- Anti adrenergic agent (Beta blockers)
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C18H31NO4
- Chemical Structure: Image of chemical structure provided
Common Questions
- What is Myocor 5 mg Tablet?
- What is Myocor 5 mg Tablet used for?
- How should I take Myocor 5 mg Tablet?
- What are the side effects of Myocor 5 mg Tablet?
- Is Myocor 5 mg Tablet safe to take?
- Should I use Myocor 5 mg Tablet empty stomach, before or after food?
- Instructions for storage and disposal of Myocor 5 mg Tablet
Quick Tips
- May cause dizziness
- Can hide symptoms of low blood sugar if diabetic
- Do not stop taking suddenly as it can cause blood pressure to rise suddenly