Xderm N (0.5 mg+5 mg+1 Lac IU)/gm (Ointment)

15 gm tube: ৳ 65.00

Medicine Details

Category	Details
Generic	Clobetasol propionate neomycin sulphate nystatin
Company	Biopharma limited
Also available as	Xderm n 05 mg cream

Indications

Short courses treatment of recalcitrant eczemas
Neurodermatoses
Psoriasis (excluding widespread plaque psoriasis) where secondary bacterial infection or fungal infection is present
Other inflammatory conditions which do not respond satisfactorily to less active steroids

Pharmacology

Clobetasol Propionate is a very potent corticosteroid for severe inflammatory skin disorders. Neomycin Sulphate is an antibiotic for treating bacterial infections. Nystatin is an antifungal for killing fungi and yeasts.

Dosage & Administration

Adults: Apply sparingly once or twice daily to affected area
Elderly: Suitable for use, caution with decreased renal function
Children: Suitable for use in children over 2 years old

Interaction

Neomycin Sulphate can intensify respiratory depressant effects of neuromuscular blocking agents

Contraindications

Contraindicated in rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections, and hypersensitivity to the preparation

Side Effects

Prolonged use can result in systemic absorption and features of hypercortisolism. Local atrophic changes, pigmentation changes, and hypertrichosis may occur.

Pregnancy & Lactation

Little information on the effects of Neomycin on pregnancy and lactation. Clobetasol Propionate safety not established in lactating mothers.

Precautions & Warnings

Avoid long-term continuous topical therapy, particularly in infants and children. Ensure the preparation does not enter the eye.

Overdose Effects

Acute overdosage is unlikely, chronic overdosage may lead to hypercortisolism features.