Amimax 100 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 16.00 (2 x 5: ৳ 160.00)

Medicine Details

Category Details
Generic Amikacin
Company Biopharma limited
Also available as
Amimax 500 mg injection

Title

  • Amimax Amikacin Injection

Categories

  • Medicine
  • Pharmaceuticals
  • Antibiotic

Description

  • Amimax is a semisynthetic aminoglycoside antibiotic used for the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. It is effective in bacterial septicemia, respiratory tract infections, bone and joint infections, central nervous system infections, skin and soft tissue infections, intra-abdominal infections, burns, postoperative infections, complicated and recurrent urinary tract infections, and staphylococci infections. It is primarily indicated for use in adults, children, neonates, and premature children.

Brand

Amimax

DosageForm

Injection

PackagingSize

Single vial

PackagingType

Glass vial

Color

Clear

Strength

100 mg

PackagingInformation

  • BoxContents: 1 vial
  • Instructions: For single use only

Pharmacology

  • Active against pseudomonas species
  • Effective in vitro against various bacteria strains

Dosage

  • RecommendedDose:
    • AdultsAndChildren: 15 mg/kg/day in two equally-divided doses
    • NeonatesAndPrematureChildren: An initial loading dose of 10 mg/kg followed by 15 mg/kg/day
    • Elderly: Dosage adjustment based on renal function
    • LifeThreateningInfections: May increase to 500 mg every eight hours
    • UrinaryTractInfections: 7.5 mg/kg/day in two equally divided doses
    • ImpairedRenalFunction: Dosage reduction and/or increased intervals between doses
  • MaximumTotalAdultDose: 15g
  • DosageDuration: Not longer than 10 days

Administration

  • Routes:
    • Intramuscular
    • Intravenous
    • Intraperitoneal
  • PreferredRoute: Intramuscular
  • SpecialCases: Intravenous route may be used in life-threatening infections

Interaction

  • Myorelaxants: Potentiation of effects
  • AminoglycosideAntibiotics: Avoid concurrent use
  • FastActingDiuretics: Increases risk of ototoxicity in renal failure patients
  • CephalosporinsOrPolymixins: Increases risk of nephrotoxicity

Contraindications

  • Hypersensitivity to Amikacin or any constituents of the injection

SideEffects

  • Tinnitus
  • Vertigo
  • Partial reversible or irreversible deafness
  • Skin rash
  • Drug fever
  • Headache
  • Paraesthesia
  • Nausea and vomiting

PregnancyAndLactation

  • Pregnancy: Potential risk of ototoxicity in the fetus
  • Lactation: Safety information not available

PrecautionsAndWarnings

Patients should be well hydrated to minimize chemical irritation of the renal tubules. Monitoring of renal function during treatment is important.

SpecialPopulations

  • PediatricUse: Safety and effectiveness not established for children or adolescents under 16 years

OverdoseEffects

Peritoneal dialysis or haemodialysis may aid in the removal of Amimax from the blood in case of overdose or toxic reaction

TherapeuticClass

Aminoglycosides

StorageConditions

Keep below 30°C temperature, away from light and moisture, out of the reach of children

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