Minipress XL 2.5 mg (Tablet (Extended Release))

Unit Price: ৳ 13.60 (2 x 15: ৳ 408.00)
Strip Price: ৳ 204.00

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Pfizer
Also available as
Minipress xl 5 mg tablet

Indications

  • Treatment of essential hypertension
  • Treatment of secondary hypertension
  • Treatment of left ventricular failure
  • Treatment of Raynaud's phenomenon and disease
  • Adjunct in symptomatic treatment of benign prostatic hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Selective inhibition of alpha-1-adrenoreceptors
  • Lowering of blood pressure in supine and standing positions
  • Reduction in left ventricular filling pressure
  • Improvement of urinary pressure profile in men with benign prostatic hyperplasia

Dosage & Administration

  • Initial therapy with a low starting dose
  • Dosage adjustment based on patient's response
  • Maintenance dosage of 20 mg for hypertension
  • Titration of dosage for left ventricular failure
  • Recommended starting dosage for Raynaud's phenomenon and disease
  • Usual maintenance dosage for benign prostatic hyperplasia

Interaction

  • No adverse drug interactions reported with cardiac glycosides, hypoglycemic agents, tranquilizers and sedatives, antiarrhythmic agents, analgesic and anti-inflammatory agents

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Nausea
  • Vomiting
  • Diarrhea
  • Liver function abnormalities
  • Edema
  • Orthostatic hypotension
  • Impotence
  • Blurred vision
  • Dry mouth
  • Nasal congestion
  • Fever
  • Rash

Pregnancy & Lactation

  • No teratogenic effects seen in animal testing
  • Use only if potential benefit justifies potential risk to mother and fetus
  • Excretion in small amounts in human milk

Precautions & Warnings

  • Caution advised for patients prone to postural hypotension
  • Careful monitoring and adjustment of diuretic dosage for left ventricular failure patients
  • Close blood pressure monitoring for patients with existing lower blood pressure
  • Not recommended for children under 12 years

Use in Special Populations

  • Not recommended for children under 12 years
  • Not recommended for left ventricular failure due to mechanical obstruction
  • Efficacy not established in left ventricular failure due to recent myocardial infarction

Overdose Effects

  • Profound drowsiness and depressed reflexes in pediatric accidental ingestion
  • Support of the cardiovascular system as first importance
  • Monitoring and support of renal function as needed

Therapeutic Class

  • Alpha adrenoceptor blocking drugs

Storage Conditions

  • Keep away from light and moisture
  • Store below 30°C
  • Keep away from reach of children

Related Brands