Broklin 50 mg (Capsule)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | One pharma ltd |
| Also available as |
Title
- Broklin 50 mg Capsule
Categories
- Medicine
- Neuropathic Pain Management
- Anticonvulsant
- Fibromyalgia Treatment
Description
- Broklin is indicated for neuropathic pain associated with diabetic peripheral neuropathy (DPN), postherpetic neuralgia (PHN), adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older, fibromyalgia, and neuropathic pain associated with spinal cord injury. The CR tablet is indicated for neuropathic pain associated with DPN and PHN.
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) for DPN with dosing beginning at 50 mg three times a day (150 mg/day)
- Recommended dose of Pregabalin for PHN is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day) for patients with creatinine clearance of at least 60 ml/min
- For fibromyalgia, the recommended dose of Pregabalin is 300 to 450 mg/day
- For neuropathic pain associated with spinal cord injury, the recommended dose range is 150 to 600 mg/day
- Route of administration: Oral
- Pregabalin CR tablet should be administered after an evening meal
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be swallowed whole and should not be split, crushed, or chewed
- When discontinuing both Pregabalin and Pregabalin CR, it should be gradually tapered over a minimum of 1 week
Interaction
- Broklin is unlikely to be involved in significant pharmacokinetic drug interactions
- Not applicable food and other drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Most common side effects in adults are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
- Most common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding is not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- Broklin should be discontinued immediately if hypersensitivity reactions occur
- Antiepileptic drugs, including Broklin, increase the risk of suicidal thoughts or behavior
- Respiratory depression may occur with Broklin when used with concomitant CNS depressants
- Broklin may cause dizziness and somnolence and impair patients' ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if Broklin is rapidly discontinued
Use in Special Populations
- Safety and effectiveness in pediatric patients have not been established for various indications
- Safety and effectiveness have not been established for pediatric patients below the age of 1 month
- Safety and effectiveness of Broklin extended-release tablet in pediatric patients have not been established
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
- General supportive care of the patient is indicated
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C), protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure: Image available
Common Questions
- Broklin 50 mg Capsule is an anticonvulsant and is considered to be the first-line of treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Should be taken till improvement is seen
- Dosage should be as prescribed by the doctor
- Should be taken after food
- Storage and disposal instructions available
- Works differently for different diseases
- Consult doctor before discontinuing
- May be used with Diazepam
- May cause weight gain
- Quick Tips: Medication should be taken as per prescribed dose and duration, may cause sleepiness, may cause vision changes, inform doctor about any unusual changes in mood or behavior, do not stop suddenly without consulting doctor