Maxpro MUPS 20 mg (MUPS Tablet)
Unit Price: ৳ 10.00 (4 x 14: ৳ 560.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole mups preparation |
| Company | Renata limited |
| Also available as |
Indications
- Gastro-esophageal Reflux Disease (GERD)
- Risk reduction in NSAID associated gastric ulcer
- H. pylori eradication (Triple therapy)
- Zollinger-Ellison syndrome and idiopathic hypersecretion
Composition
- 20 mg Esomeprazole MUPS tablet
- 40 mg Esomeprazole MUPS tablet
- Esomeprazole enteric coated pellets equivalent to 20 mg Esomeprazole
- Esomeprazole enteric coated pellets equivalent to 40 mg Esomeprazole
- Esomeprazole Magnesium Trihydrate USP
- 133.333 mg (15%w/w) of Esomeprazole enteric coated pellets
Description
- MUPS - Multiple-Unit Pellet System
- Compaction of modified release coated multiparticulates into tablets
- Greater bioavailability
- Uniform emptying of micro pellets from stomach into small intestine
- Rapid dissolution of enteric coating
- Combines advantages of tablets and pellet-filled capsules
- Fast acting and sustained action
- Once daily dosing
- Better and more uniform drug absorption
- Rapid and uniform gastric emptying
- Consistent and controlled pharmacological action
Pharmacology
- Inhibition of gastric acid by blocking the proton pump
- Effective for short-term treatment of gastric and duodenal ulcers
- Prevention and treatment of NSAID associated gastric ulcers
Dosage
- 40 mg once daily for 4 weeks (Adult)
- 20 mg once daily (Adult)
- 20 mg twice daily for 7 days (Adult)
- 40-80 mg twice daily (Adult)
- 10 mg once daily for 8 weeks (Children <11 years)
Administration
- Swallow whole with liquid
- Can be dispersed in non-carbonated water
- Stir until tablets disintegrate
Interaction
- Metabolized in the liver by CYP2C19 and CYP3A4
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
- Potential interference with CYP2C19
- Inhibition of gastric acid secretion
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- Manufacturer advises caution
- Unknown presence in human breast milk
Precautions & Warnings
- Use with caution in severe liver dysfunction and severe renal impairment
- Slight increase in risk of hip, wrist and spine fracture
Storage Conditions
- Store below 25°C
- Protect from light
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
Common Questions about Maxpro MUPS 20 mg Tablet
- Proton pump inhibitor
- Reduces stomach acid production
- Used for GERD, ulcers, and conditions related to excess stomach acid
- Common side effects such as headaches and nausea
- Caution advised during pregnancy and breastfeeding
- Maximum efficacy within a few hours