Maxpro MUPS 20 mg (MUPS Tablet)

Unit Price: ৳ 10.00 (4 x 14: ৳ 560.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Esomeprazole mups preparation
Company Renata limited
Also available as
Maxpro mups 40 mg tablet

Indications

  • Gastro-esophageal Reflux Disease (GERD)
  • Risk reduction in NSAID associated gastric ulcer
  • H. pylori eradication (Triple therapy)
  • Zollinger-Ellison syndrome and idiopathic hypersecretion

Composition

  • 20 mg Esomeprazole MUPS tablet
  • 40 mg Esomeprazole MUPS tablet
  • Esomeprazole enteric coated pellets equivalent to 20 mg Esomeprazole
  • Esomeprazole enteric coated pellets equivalent to 40 mg Esomeprazole
  • Esomeprazole Magnesium Trihydrate USP
  • 133.333 mg (15%w/w) of Esomeprazole enteric coated pellets

Description

  • MUPS - Multiple-Unit Pellet System
  • Compaction of modified release coated multiparticulates into tablets
  • Greater bioavailability
  • Uniform emptying of micro pellets from stomach into small intestine
  • Rapid dissolution of enteric coating
  • Combines advantages of tablets and pellet-filled capsules
  • Fast acting and sustained action
  • Once daily dosing
  • Better and more uniform drug absorption
  • Rapid and uniform gastric emptying
  • Consistent and controlled pharmacological action

Pharmacology

  • Inhibition of gastric acid by blocking the proton pump
  • Effective for short-term treatment of gastric and duodenal ulcers
  • Prevention and treatment of NSAID associated gastric ulcers

Dosage

  • 40 mg once daily for 4 weeks (Adult)
  • 20 mg once daily (Adult)
  • 20 mg twice daily for 7 days (Adult)
  • 40-80 mg twice daily (Adult)
  • 10 mg once daily for 8 weeks (Children <11 years)

Administration

  • Swallow whole with liquid
  • Can be dispersed in non-carbonated water
  • Stir until tablets disintegrate

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
  • Potential interference with CYP2C19
  • Inhibition of gastric acid secretion

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • Manufacturer advises caution
  • Unknown presence in human breast milk

Precautions & Warnings

  • Use with caution in severe liver dysfunction and severe renal impairment
  • Slight increase in risk of hip, wrist and spine fracture

Storage Conditions

  • Store below 25°C
  • Protect from light
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Maxpro MUPS 20 mg Tablet

  • Proton pump inhibitor
  • Reduces stomach acid production
  • Used for GERD, ulcers, and conditions related to excess stomach acid
  • Common side effects such as headaches and nausea
  • Caution advised during pregnancy and breastfeeding
  • Maximum efficacy within a few hours

Related Brands