Vericox 60 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Veritas pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Rheumatoid arthritis (RA)
- Ankylosing spondylitis
- Pain and signs of inflammation associated with acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active COX-2 specific inhibitor
- Inhibition of COX-2 decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation
- Dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily
Dosage & Administration
- Recommended dose for Osteoarthritis is 30 mg once daily, may increase to 60 mg if insufficient relief
- Recommended dose for Rheumatoid arthritis and Ankylosing spondylitis is 90 mg once daily
- Recommended dose for Acute gouty arthritis is 120 mg once daily for 8 days
- Recommended dose for Postoperative dental surgery pain is 90 mg once daily, limited to a maximum of 3 days
Interaction
- Interaction with oral anticoagulants, diuretics, ACE inhibitors, angiotensin II antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, and lithium
- Take without regards to meals
Contraindications
- Hypersensitivity to the active substance or any of the excipients
- Active peptic ulceration or active gastrointestinal (GI) bleeding
- Pregnancy and lactation
- Severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min
- Inflammatory bowel disease, congestive heart failure, hypertension, established ischaemic heart disease, peripheral arterial disease, or cerebrovascular disease
Side Effects
- Palpitation, fatigue, influenza-like symptoms, ecchymosis
- Less commonly dry mouth, taste disturbance, mouth ulcer, appetite and weight change
- Very rarely confusion and hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Not known whether excreted in human milk, not recommended for breastfeeding women
Precautions & Warnings
- Caution in patients at risk of developing gastrointestinal complications with NSAIDs, significant risk factors for cardiovascular events
- Monitoring of renal function in patients with impaired renal function
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function, discontinuation in case of hepatic insufficiency or signs of hypersensitivity
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- Single doses up to 500 mg and multiple doses up to 150 mg/day for 21 days did not result in significant toxicity
- Employ usual supportive measures in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store at a temperature below 30°C, protect from light and moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Duration of Effect
20-24 hours
Onset of Action
Within 1-2 hours of administration, faster if taken without food
Pregnancy Warnings
Consult doctor before use
Habit Forming
No
Breast-feeding Warnings
Not recommended, consult doctor before use
Safe with Alcohol
Unsafe
Safety for Driving
May affect alertness, avoid driving
Kidney Function
Caution and dose adjustment in kidney disease, strictly not recommended in severe kidney disease
Liver Function
Caution and dose adjustment in liver disease, strictly not recommended in severe liver disease
Quick Tips
- Helps relieve pain and inflammation
- May cause fewer stomach problems compared to other NSAIDs like Ibuprofen or Naproxen
- May cause dizziness and fatigue, do not drive or operate machinery
- Avoid alcohol consumption
- Regular monitoring of blood pressure, liver function tests
- Not recommended in pregnancy, planning to conceive, or breastfeeding