Doxofyl SR 400 mg (Tablet (Sustained Release))
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Selectively inhibits phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Inhibits platelet activating factor (PAF)
- Decreased affinities toward adenosine A1 and A2 receptors
Dosage & Administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily
- Children:
- >12 years of age: 10 ml syrup or 200 mg tablet two or three times daily
- 6-12 years of age: 6-9 mg/kg body weight two times daily
Interaction
- Avoid administration with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Exercise caution with ephedrine or other sympathomimetic drugs
- Concurrent administration of certain drugs may affect hepatic clearance
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Tachycardia
- Tachypnea
- Insomnia
- Hyperglycemia (rare)
Pregnancy & Lactation
- Consider evaluation of risk-benefit ratio for use during pregnancy
- Contraindicated during lactation
- No sufficient clinical evidence about effects during pregnancy
Precautions & Warnings
- Factors may reduce hepatic clearance and increase plasma levels
- Caution in patients with cardiac disease, hypertension, severe hypoxemia, hyperthyroidism
- Monitoring of blood levels recommended in certain cases
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children. Should be used only on prescription of specialist physician