Asidox 100 mg (Capsule)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Asiatic laboratories ltd |
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Description
- Highly active broad-spectrum antibiotic
- Effective against Gram-positive and Gram-negative bacteria
- Effective against spirochete, mycoplasma, rickettsia, and mycobacteria
- Used as an alternative to penicillin in the treatment of gonorrhea and syphilis
- Main mechanism of action on protein synthesis
Pharmacology
- Semisynthetic tetracycline antibiotic with broad-spectrum activity
- Primarily a bacteriostatic antibiotic
- More active against Staphylococcus aureus and Nocardia
- Active against penicillin-resistant strains of Staphylococcus aureus
- Active against certain Gram-negative strains of E. coli, Proteus mirabilis, and Klebsiella
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Absorption impaired by antacids containing aluminum, calcium, or magnesium
- Absorption impaired by iron-containing preparations
- Absorption impaired by bismuth salicylate
- Barbiturates, carbamazepine, and phenytoin decrease half-life of doxycycline
- Concurrent use may render oral contraceptives less effective
Contraindications
- Hypersensitivity to tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hemolytic anemia
- Eosinophilia
Pregnancy & Lactation
- Avoided in pregnant women
- Enter breast milk, mothers taking should not breastfeed
Precautions & Warnings
- Avoid use during tooth development
- May cause permanent discoloration of teeth
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place, protected from light