Osmosol 20% (IV Infusion)

500 ml bottle: ৳ 155.00

Medicine Details

Category	Details
Generic	Mannitol
Company	Beximco pharmaceuticals ltd

Title

Osmosol Intravenous Infusion

Description

Clear, colorless sterile solution of Osmosol BP 20g, used to preserve renal function, reduce intracranial and intraocular pressure, prevent hemolysis, manage acute drug poisoning, provide symptomatic relief for various conditions, and as a prophylactic in renal failure.

Indications

Renal insufficiency
Reperfusion injury
Raised intracranial pressure
Bladder irrigation
Raised intraocular pressure
Bowel preparation
Edematous status
Management of poisoning
Termination of Pregnancy

DosageAndAdministration

Adults:
- 50-100g by IV infusion
- adjust rate to maintain urine flow of 30-50 ml/hr
Children:
- 2g/kg or 60g/m^2 of body surface area
- varies with specific condition being treated

Contradictions

Pulmonary edema or congestive heart failure
Inadequate urine flow
Dehydration or acidosis
Intracranial bleeding
Renal failure unless test dose produces diuretic response

SideEffects

Fluid and electrolytes imbalance
Circulatory overload
Acidosis at high doses
Nausea
Vomiting
Thirst
Headache
Dizziness
Fever
Tachycardia
Chest pain
Hyponatremia
Dehydration
Blurred vision
Urticaria
Hypertension or hypotension

PregnancyAndLactation

Safety not established; administer after careful risk-benefit evaluation

PrecautionsAndWarnings

Monitor rate of administration to prevent fluid and electrolyte imbalance
Discontinue if signs of renal dysfunction, heart failure or pulmonary congestion develop
Do not administer with whole blood
Discontinue infusion if rigor arises for any reason
Do not use if solution is cloudy, contains particles, or after expiry date

TherapeuticClass

Osmotic diuretics

StorageConditions

Store at 20°C to 30°C; avoid exposure to lower temperatures, warm to dissolve crystals, use promptly after opening, discard unused contents